Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
D2975000
ドキソルビシン 塩酸塩
European Pharmacopoeia (EP) Reference Standard
別名:
DOX, アドリアマイシン® 塩酸塩, ヒドロキシダウノルビシン 塩酸塩
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About This Item
おすすめの製品
グレード
pharmaceutical primary standard
APIファミリー
doxorubicin
メーカー／製品名
EDQM
mp
216 °C (dec.) (lit.)
アプリケーション
pharmaceutical (small molecule)
フォーマット
neat
SMILES記法
Cl[H].COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(=O)CO
InChI
1S/C27H29NO11.ClH/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34;/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3;1H/t10-,13-,15-,17-,22+,27-;/m0./s1
InChI Key
MWWSFMDVAYGXBV-RUELKSSGSA-N
遺伝子情報
human ... TOP2A(7153)
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関連するカテゴリー
詳細
アプリケーション
Established for the preparation of the below-given solutions as per European Pharmacopoeia:
- Reference solutions (b) and (c) in the testing of related substances in daunorubicin hydrochloride using liquid chromatography (General text 2.2.29), according to the monograph 0662
- Reference solutions (a) and (c) to test related substances in doxorubicin hydrochloride using liquid chromatography (General text 2.2.29), according to the monograph 0714
- Reference solutions (b) and (c) in the testing of related substances in epirubicin hydrochloride using liquid chromatography (General text 2.2.29), according to the monograph 1590
包装
その他情報
シグナルワード
Danger
危険有害性情報
危険有害性の分類
Acute Tox. 4 Oral - Carc. 1B - Muta. 1B - Repr. 1B
保管分類コード
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
D2975000-1EA:
D2975000:
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How is shipping temperature determined? And how is it related to the product storage temperature?
1 回答-
役に立ちましたか？
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How can I determine the shelf life / expiration / retest date of this product?
1 回答-
If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf役に立ちましたか？
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può gentilmente dirmi se questo prodotto si può utilizzare per esperimenti sul topo?
1 回答-
This product is intended for use as an analytical standard and has not been tested for use in other applications. Currently, there is no Doxorubicin HCl product available that has been tested for in vivo or in vitro use. However, the research grade item, D1515, has been used successfully in mice, as cited in several publications. Please see the links below to review articles that may be of interest:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7451836/pdf/PAN_2020_v24n2_11.pdf
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4036477/役に立ちましたか？
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アクティブなフィルタ
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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