60634

カタラーゼ Micrococcus lysodeikticus由来

solution, dark brown

• CAS番号: 9001-05-2
• MDL番号: MFCD00081483
• UNSPSCコード: 12352204
• NACRES: NA.54

特性

• 由来生物: bacterial (Micrococcus lysodeikticus)
• 品質水準: 200
• フォーム: solution
• 比活性: 65,000-150,000 U/mL
• 分子量: M_r ~230000
• テクニック: microbe id | metabolite detection: suitable
• 色: dark brown
• 溶解性: 0.05 M phosphate buffer pH 7.0: soluble, clear, brown (1:10)
• タンパク質IDアクセッション番号: UTX35086
• UniProtアクセッション番号: P29422
• 輸送温度: wet ice
• 保管温度: 2-8°C
• SMILES記法: O(CC)C(=O)c1ccc(cc1)O
• InChI: 1S/C9H10O3/c1-2-12-9(11)7-3-5-8(10)6-4-7/h3-6,10H,2H2,1H3
• InChI Key: NUVBSKCKDOMJSU-UHFFFAOYSA-N

詳細

詳細

Research area: Cell Signaling

Catalase (CAT) is an antioxidant enzyme, encoded by the CAT gene family. The enzyme is ubiquitously expressed in most of the aerobic organisms.[1]

アプリケーション

Catalase from Micrococcus lysodeikticus has been used to eliminate excess of hydrogen peroxide production during sugar analog synthesis by in vitro biocatalytic cascade.[2] It has also been used as a standard to evaluate oxidative stress by indirectly measuring catalytic activity.[3][4][5]

生物化学的／生理学的作用

Catalase rapidly converts hydrogen peroxide to oxygen and water.[6] It exhibits antioxidant activity and elicits a defense mechanism against reactive oxygen species (ROS). Catalase plays a role in neutralizing noxious hydrogen peroxide in nature as well as in various industries such as textile, pharma, and dairy.[7] Micrococcus lysodeikticus catalase is a heme-containing protein.[5]Catalase, along with various key cellular systems involved in hydrogen peroxide (H₂O₂) processing, plays a key role in regulating cellular redox balance and aids in cellular and intercellular signaling.[8]

単位の定義

1 unitは、pH 7.0、25°C、1分間で、1 μmolのH₂O₂を分解する酵素量に相当します。

安全性情報

• ピクトグラム: GHS08
• シグナルワード: Danger
• 危険有害性情報: H334
• 注意書き: P261 - P284 - P501
• 危険有害性の分類: Resp. Sens. 1
• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves