484235

p-Nitroblue Tetrazolium Chloride

≥98% (TLC), crystalline solid, nitric oxide synthase inhibitor, Calbiochem^®

• 別名: p-Nitroblue Tetrazolium Chloride, NBT, Nitro BT
• 実験式（ヒル表記法）: C₄₀H₃₀Cl₂N₁₀O₆
• CAS番号: 298-83-9
• 分子量: 817.64
• MDL番号: MFCD00012159
• UNSPSCコード: 12171500
• NACRES: NA.77

特性

• 製品名: p-Nitroblue Tetrazolium Chloride, NADPH-diaphorase substrate that competitively inhibits nitric oxide synthase (IC₅₀ = 3-4 µM).
• 品質水準: 100
• 詳細: RTECS - XF8045000
• アッセイ: ≥98% (TLC)
• フォーム: crystalline solid
• 有効性: 3-4 μM IC₅₀
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze; desiccated (hygroscopic); protect from light
• 色: yellow
• 溶解性: methanol: soluble; water: soluble
• 輸送温度: ambient
• 保管温度: 2-8°C
• SMILES記法: [Cl-].[Cl-].[n+]2([n](nc(n2)c8ccccc8)c3c(cc(cc3)c4cc(c(cc4)[n]5[n+](nc(n5)c7ccccc7)c6ccc(cc6)[N+](=O)[O-])OC)OC)c1ccc(cc1)[N+](=O)[O-]
• InChI: 1S/C40H30N10O6.2ClH/c1-55-37-25-29(13-23-35(37)47-43-39(27-9-5-3-6-10-27)41-45(47)31-15-19-33(20-16-31)49(51)52)30-14-24-36(38(26-30)56-2)48-44-40(28-11-7-4-8-12-28)42-46(48)32-17-21-34(22-18-32)50(53)54;;/h3-26H,1-2H3;2*1H/q+2;;/p-2
• InChI Key: FSVCQIDHPKZJSO-UHFFFAOYSA-L

詳細

詳細

NADPH-diaphorase substrate that competitively inhibits nitric oxide synthase (IC₅₀ = 3-4 µM). A well-known scavenger of superoxide anions. Useful as a substrate for alkaline phosphatase, often in conjunction with BCIP (Cat. No. 203788).

生物化学的／生理学的作用

Primary Target
NOS

警告

Toxicity: Harmful (C)

再構成

Following reconstitution, aliquot and freeze (-20°C) for long-term storage or refrigerate (4°C) for short-term storage.

その他情報

Pistelli, A., et al. 1994. Biochem. Pharmacol. 47, 1737.
De la Fuente, M., et al. 1993. Comp. Immunol. Microbiol. Infect. Dis.16, 29.
Libon, C., et al. 1993. J. Leukoc. Biol.53, 93.
Mittal, C.K. 1993. Biochem. Biophys. Res. Commun. 193, 126.
Nichols, K., et al. 1992. Neuroscience51, 791.
Nichols, K., et al. 1992. Neuroscience51, 791.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H302,H315,H319,H335
• 注意書き: P261 - P264 - P271 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• 危険有害性の分類: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• ターゲットの組織: Respiratory system
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable