1.03669

グリシン

granulated, EMPROVE^® EXPERT, Ph. Eur., BP, ChP, JP, USP

• 別名: アミノエタン酸, アミノ酢酸, グリココール
• 化学式: NH₂CH₂COOH
• CAS番号: 56-40-6
• 分子量: 75.07
• Beilstein: 635782
• MDL番号: MFCD00008131
• UNSPSCコード: 12352209
• EC Index Number: 200-272-2

特性

• 認証: BP; ChP; JP; Ph. Eur.; USP
• 品質水準: 500
• 蒸気圧: 0.0000171 Pa ( 25 °C)
• 詳細: granulated EMPROVE^® EXPERT Ph.Eur.,BP,JP,USP
• 製品種目: EMPROVE^® EXPERT
• アッセイ: 99.0-101.0% (calculated on dried substance, perchloric acid titration)
• フォーム: granular
• テクニック: inhibition assay: suitable
• pH: 5.9-6.4 (20 °C, 50 g/L in H₂O)
• pKa (25 °C): (1) 2.35, (2) 9.60; 2.35
• mp: 240 °C (dec.) (lit.)
• 密度: 1.161 g/cm³ at 20 °C
• アプリケーション: liquid formulation; parenterals; pharma/biopharma processes; pharmaceutical
• 保管温度: 2-30°C
• SMILES記法: NCC(O)=O
• InChI: 1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
• InChI Key: DHMQDGOQFOQNFH-UHFFFAOYSA-N

詳細

詳細

Standard bulk materials often show a tendency for caking, clumping and dust formation which results in laborious weighing processes and manual de-caking processes with a negative impact on manufacturing efficiency. Due to its granulated form, granulated glycine is free-flowing and easy to handle. Its greatly reduced caking behavior facilitates processability, speeds up manufacturing processes and increases operator safety.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

アプリケーション

Glycine in general is widely used in the biopharma industry as a stabilizer, tonicity modifier, buffer and precipitating agent. It is also used as an emollient, emulsifying agent and solubilizer in solid and semi-solid formulations.
Due to its low microbial and endotoxin limits, Glycine granulated Emprove^® Expert is especially suitable for high-risk applications.

生物化学的／生理学的作用

脊髄における抑制性神経伝達物質であり、NMDAレセプターのアロステリック調節因子です。

法的情報

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable