850356C

4ME 16:0 PC

Avanti Research^™ - A Croda Brand

• Sinonimo/i: 1,2-di-(3,7,11,15-tetramethylhexadecanoyl)-sn-glycero-3-phosphocholine; PC(16:0(3me,7me,11me,15me)/16:0(3me,7me,11me,15me))
• Formula empirica (notazione di Hill): C₄₈H₉₆NO₈P
• Numero CAS: 207131-40-6
• Peso molecolare: 846.25
• Numero MDL: MFCD00674308
• Codice UNSPSC: 51191904
• NACRES: NA.25

Proprietà

• Descrizione: 1,2-diphytanoyl-sn-glycero-3-phosphocholine, chloroform
• Saggio: >99% (TLC)
• Stato: liquid
• Confezionamento: pkg of 1 × 2.5 mL (850356C-25mg); pkg of 1 × 20 mL (850356C-500mg); pkg of 2 × 4 mL (850356C-200mg)
• Produttore/marchio commerciale: Avanti Research^™ - A Croda Brand
• Concentrazione: 10 mg/mL (850356C-25mg); 25 mg/mL (850356C-200mg); 25 mg/mL (850356C-500mg)
• Condizioni di spedizione: dry ice
• Temperatura di conservazione: −20°C

Descrizione

Descrizione generale

4ME 16:0 PC/DPhPC (1,2-diphytanoyl-sn-glycero-3-phosphocholine is a synthetic lipid.[1] It has ester linkages between acyl chains and glycerol backbone and also between the headgroup and glycerol backbone.[2] This neutral lipids possess high steric asymmetry.[3] It remains in fluid or viscous liquid crystalline state over a wide range of temperature.[1]

Lipids containing diphytanoyl fatty acid chains have been used to produce stable planar lipid membranes (see References). Diphytanoyl phosphatidylcholine does not exhibit a detectable gel to liquid crystalline phase transition from -120°C to +120°C.The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products from oxidization and hydrolysis.

Applicazioni

4ME 16:0 PC is suitable for use:

• to study its phase behaviour and its interactions with the representative antimicrobial peptide PGLa from Xenopus laevis (peptidyl-glycylleucine-carboxyamide[1]
• to improve the mechanical stability of planar lipid bilayer membrane[2]
• to prepare giant unilamellar vesicles (GUVs)[3]

Azioni biochim/fisiol

4ME 16:0 PC/DPhPC (1,2-diphytanoyl-sn-glycero-3-phosphocholine can be used as a bilayer mimic for electrophysiological measurements.[1] It is stable under mechanical stress but the ester linkages are liable to hydrolysis under acidic or alkaline conditions.[2]

Confezionamento

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (850356C-500mg)

5 mL Clear Glass Sealed Ampule (850356C-200mg)

5 mL Clear Glass Sealed Ampule (850356C-25mg)

Note legali

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informazioni sulla sicurezza

• Pittogrammi: GHS06,GHS08
• Avvertenze: Danger
• Indicazioni di pericolo: H302,H315,H319,H331,H336,H351,H361d,H372,H412
• Consigli di prudenza: P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313
• Classi di pericolo: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• Organi bersaglio: Central nervous system, Liver,Kidney
• Codice della classe di stoccaggio: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable