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DRD2

dopamine receptor D2

Sinonimi:

D2DR, D2R

Specie:

Human DRD2 (1813), Mouse Drd2 (13489), Rat Drd2 (24318), dog DRD2 (403701), Domestic Rabbit DRD2 (100347371), Horse DRD2 (100062195), naked mole-rat Drd2 (101711462), sheep DRD2 (101113525), chicken DRD2 (428252), domestic guinea pig Drd2 (100732584) ...Più

ID UniProtKB:

P14416, Q9NZR3, Q9UPA9

ID gene:

Human(1813) Summary: This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing. [provided by RefSeq, Jul 2008]
Mouse(13489) dopamine receptor D2
Rat(24318) dopamine receptor D2
dog(403701) dopamine receptor D2
Domestic Rabbit(100347371) dopamine receptor D2
Horse(100062195) dopamine receptor D2
naked mole-rat(101711462) dopamine receptor D2
sheep(101113525) dopamine receptor D2
chicken(428252) dopamine receptor D2
domestic guinea pig(100732584) dopamine receptor D2
cow(281126) dopamine receptor D2
domestic cat(101096838) dopamine receptor D2

Prodotti (185)
Documenti “peer reviewed” (838)

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Small Molecule - Agonist

Numero di prodotto

Descrizione

Specie

Cabergoline, ≥98% (HPLC),

Specie

human

Cabergoline, United States Pharmacopeia (USP) Reference Standard,

Specie

human

Q111

(±)-Quinpirole dihydrochloride, powder,

Specie

human

P102

R(+)-3-(3-Hydroxyphenyl)-N-propylpiperidine hydrochloride, solid,

Specie

human

Q102

(−)-Quinpirole hydrochloride, ≥98% (HPLC), solid,

Specie

human

Small Molecule - Antagonist

Numero di prodotto

Descrizione

Specie

Tyramine, ≥98.0%,

Specie

rat

Prochlorperazine dimaleate salt, ,

Specie

human

E101

S-(−)-Eticlopride hydrochloride, ≥98% (HPLC), powder,

Specie

human

R121

S(−)-Raclopride (+)-tartrate salt, >97%, solid,

Specie

human

Fluphenazine Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,

Specie

human

Antibodies

Numero di prodotto

Descrizione

Reattività con

Applicazione

Anti-Dopamine D2 Receptor Antibody, serum, Chemicon^®,

Reattività con

rat

Applicazione

ELISA
immunocytochemistry
immunohistochemistry
western blot

Anti-Dopamine D2 Receptor Antibody, from rabbit, purified by affinity chromatography,

Reattività con

mouse

Applicazione

immunohistochemistry

Anti-DRD2, affinity isolated antibody,

Reattività con

human

Applicazione

immunohistochemistry

Monoclonal Anti-DRD2, (N-terminal) antibody produced in mouse, clone 1B11, ascites fluid,

Reattività con

human

Applicazione

ELISA
western blot

Anti-Dopamine D_2S Receptor Rabbit pAb, lyophilized, Calbiochem^®,

Reattività con

human, rat

Applicazione

Small Molecule - Inhibitor

Numero di prodotto

Descrizione

Specie

2-Bromo-α-ergocryptine methanesulfonate salt, solid,

Specie

human

D052

GBR 12909 dihydrochloride, solid, ≥98% (HPLC),

Specie

human

P127

(+)-Pentazocine, solid,

Specie

rat, human

B102

Bupropion hydrochloride, ≥98% (HPLC), solid,

Specie

human

(±)-Sulpiride, ,

Specie

human

Small Molecule - Ligand

Numero di prodotto

Descrizione

Specie

Cinnarizine, powder,

Specie

human

Small Molecule - Metabolite

Numero di prodotto

Descrizione

Specie

3-Hydroxy-4-methoxyphenethylamine hydrochloride, ,

Specie

human

3-Methoxytyramine hydrochloride, ≥95.5%, crystalline,

Specie

human

Small Molecule - Precursor

Numero di prodotto

Descrizione

Specie

3,4-Dihydroxy-L-phenylalanine, ≥98% (TLC),

Specie

mouse, human, rat

3,4-Dihydroxy-DL-phenylalanine, ,

Specie

mouse, human, rat

esiRNA

Numero di prodotto

Descrizione

Specie

MISSION^® esiRNA, targeting human DRD2,

Specie

human