1458009

Neomycin sulfate

United States Pharmacopeia (USP) Reference Standard

• Szinonimák: Neomycin trisulfate salt, Neomycin B sulfate
• Tapasztalati képlet (Hill-képlet): C₂₃H₄₆N₆O₁₃ · 3H₂SO₄
• CAS-szám: 1405-10-3
• Molekulatömeg: 908.88
• MDL-szám: MFCD00037007
• UNSPSC kód: 41116107
• NACRES: NA.24

Tulajdonságok

• grade: pharmaceutical primary standard
• API-család: neomycin
• gyártó/kereskedő neve: USP
• alkalmazás(ok): pharmaceutical (small molecule)
• Formátum: neat
• SMILES string: [S](=O)(=O)(O)O.N[C@H]1[C@H](O[C@@H]([C@H]([C@@H]1O)O)CN)O[C@H]2[C@@H]([C@H]([C@@H](C[C@@H]2N)N)O)O[C@@H]3O[C@@H]([C@H]([C@H]3O)OC4O[C@H]([C@H]([C@@H]([C@H]4N)O)O)CN)CO
• InChI: 1S/C23H46N6O13.H2O4S/c24-2-7-13(32)15(34)10(28)21(37-7)40-18-6(27)1-5(26)12(31)20(18)42-23-17(36)19(9(4-30)39-23)41-22-11(29)16(35)14(33)8(3-25)38-22;1-5(2,3)4/h5-23,30-36H,1-4,24-29H2;(H2,1,2,3,4)/t5-,6+,7-,8+,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,19-,20-,21-,22?,23+;/m1./s1
• Nemzetközi kémiai azonosító kulcs: OIXVKQDWLFHVGR-GQTDVWSESA-N

Leírás

Általános leírás

Neomycin Sulfate is the sulfate salt of a kind of neomycin, an antibacterial substance produced by the growth of Streptomyces fradiae Waksman (Fam. Streptomycetaceae), or a mixture of two or more such salts, the main component being neomycin B sulfate. It has a potency equivalent to NLT 600 µg of neomycin/mg, calculated on the dried basis.
Neomycin sulfate USP reference standard is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets, has been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Alkalmazás

Neomycin sulfate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Neomycin Sulfate Tablets
• Neomycin Sulfate Cream
• Neomycin Sulfate Ointment
• Neomycin Sulfate Ophthalmic Ointment
• Neomycin Sulfate Oral Solution
• Neomycin Sulfate and Hydrocortisone Cream

Vigyázat

Stock solutions should be filter sterilized and stored at 2-8°C, and are stable at 37°C for 5 days. A 1 mg/mL neomycin solution in .1 M phosphate buffer, pH 8.0 should be used within 14 days when stored at 0-5°C. Solutions should be protected from light or moisture.

Elkészítési megjegyzés

Neomycin sulfate is soluble in H₂O at 50 mg/mL, yielding a clear solution.

Egyéb megjegyzések

This product is part of the USP Biologics program.

Jogi információk

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Biztonsági adatok

• Piktogramok: GHS08
• Figyelmeztetés: Danger
• Figyelmeztető mondatok: H317,H334
• Óvintézkedésre vonatkozó mondatok: P261 - P272 - P280 - P284 - P302 + P352 - P333 + P313
• Veszélyességi osztályok: Resp. Sens. 1 - Skin Sens. 1
• Tárolási osztály kódja: 11 - Combustible Solids
• WGK: WGK 3
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable