1154004

Cyclizine hydrochloride

United States Pharmacopeia (USP) Reference Standard

• Szinonimák: 1-Benzhydryl-4-methylpiperazine hydrochloride, Marezine hydrochloride
• Tapasztalati képlet (Hill-képlet): C₁₈H₂₂N₂ · HCl
• CAS-szám: 303-25-3
• Molekulatömeg: 302.84
• MDL-szám: MFCD00023293
• UNSPSC kód: 41116107
• NACRES: NA.24

Tulajdonságok

• grade: pharmaceutical primary standard
• API-család: cyclizine
• gyártó/kereskedő neve: USP
• alkalmazás(ok): pharmaceutical (small molecule)
• Formátum: neat
• tárolási hőmérséklet: 2-8°C
• SMILES string: [Cl-].N3(CCN(CC3)C)C(c2ccccc2)c1ccccc1.[H+]
• InChI: 1S/C18H22N2.ClH/c1-19-12-14-20(15-13-19)18(16-8-4-2-5-9-16)17-10-6-3-7-11-17;/h2-11,18H,12-15H2,1H3;1H
• Nemzetközi kémiai azonosító kulcs: UKPBEPCQTDRZSE-UHFFFAOYSA-N

Leírás

Általános leírás

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Alkalmazás

• Apoptotic pathways in macrophages: Cyclizine hydrochloride was studied for its ability to induce cytotoxicity and apoptosis in macrophages through both extrinsic and intrinsic pathways, suggesting its potential implications in immunomodulatory therapies (Lu et al., 2024).


• Chemometric methods in impurity analysis: Advanced chemometric methods have been employed to determine cyclizine hydrochloride along with other compounds in pharmaceutical products, highlighting its importance in ensuring the purity and efficacy of drug formulations (Saad et al., 2022).


• Anti-inflammatory effects in pharmacology: Cyclizine derivatives were synthesized and evaluated for anti-inflammatory performance on Wistar rats, providing insights into the therapeutic potential of cyclizine modifications in treating inflammation (Ahmadi et al., 2012).

Analízis megjegyzés

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Egyéb megjegyzések

Sales restrictions may apply.

Biztonsági adatok

• Piktogramok: GHS06
• Figyelmeztetés: Danger
• Figyelmeztető mondatok: H301
• Óvintézkedésre vonatkozó mondatok: P264 - P270 - P301 + P310 - P405 - P501
• Veszélyességi osztályok: Acute Tox. 3 Oral
• Tárolási osztály kódja: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable