1046056

Azithromycin

United States Pharmacopeia (USP) Reference Standard

• Szinonimák: Azithromycin dihydrate, 1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10- trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylohexopyranosyl]oxy]-, [2R-(2R, 3S, 4R, 5R, 8R, 10R, 11R, 12S, 13S, 14R)]- dihydrate, N-Methyl-11-aza-10-deoxo-10-dihydroerythromycin A, CP-62993
• Tapasztalati képlet (Hill-képlet): C₃₈H₇₂N₂O₁₂ · 2H₂O
• CAS-szám: 117772-70-0
• Molekulatömeg: 785.02
• MDL-szám: MFCD01862248
• UNSPSC kód: 41116107
• PubChem Substance ID: 329749090
• NACRES: NA.24

Tulajdonságok

• grade: pharmaceutical primary standard
• Ügynökség: USP
• API-család: azithromycin
• gyártó/kereskedő neve: USP
• alkalmazás(ok): pharmaceutical (small molecule)
• format: neat
• SMILES string: O.O.CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]3O[C@H](C)C[C@@H]([C@H]3O)N(C)C)[C@](C)(O)C[C@@H](C)CN(C)[C@H](C)[C@@H](O)[C@]1(C)O
• InChI: 1S/C38H72N2O12.2H2O/c1-15-27-38(10,46)31(42)24(6)40(13)19-20(2)17-36(8,45)33(52-35-29(41)26(39(11)12)16-21(3)48-35)22(4)30(23(5)34(44)50-27)51-28-18-37(9,47-14)32(43)25(7)49-28;;/h20-33,35,41-43,45-46H,15-19H2,1-14H3;2*1H2/t20-,21-,22+,23-,24-,25+,26+,27-,28+,29-,30+,31-,32+,33-,35+,36-,37-,38-;;/m1../s1
• Nemzetközi kémiai azonosító kulcs: SRMPHJKQVUDLQE-KUJJYQHYSA-N

Leírás

Általános leírás

Azithromycin is a subclass of macrolides consisting of 15-membered macrocyclic lactone ring to which sugar moieties are linked.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Alkalmazás

Azithromycin USP reference standard for use in specified quality tests and assays.

Also used to prepare standard, standard stock solutions for the assay, identification, performance, and impurity analysis according to the given below monographs of United States Pharmacopeia (USP):

• Azithromycin for Oral Suspension
• Azithromycin Capsules
• Azithromycin for Injection

Biokémiai/fiziológiai hatások

Azithromycin dihydrate is a macrolide antibiotic, azalide subclass. It binds to the 50S subunit of the 70S bacterial ribosomes and inhibits RNA-dependent protein synthesis in bacterial cells. Azithromycin also has anti-immunomodulatory/anti-inflammatory properties, which make it useful in treating cystic fibrosis.

Analízis megjegyzés

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Egyéb megjegyzések

USP issued SDS can be found here

Sales restrictions may apply.

Biztonsági adatok

• Tárolási osztály kódja: 11 - Combustible Solids
• WGK: WGK 3
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable