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T3251

Sigma-Aldrich

(±)-α-Tocopherol

synthetic, ≥96% (HPLC)

Szinonimák:

DL-all-rac-α-Tocopherol, Vitamin E

Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez
Összes fotó(2)

About This Item

Tapasztalati képlet (Hill-képlet):
C29H50O2
CAS-szám:
10191-41-0
Molekulatömeg:
430.71
Beilstein:
94012
EC-szám:
233-466-0
MDL-szám:
MFCD00006848
UNSPSC kód:
12352205
eCl@ss:
34058016
PubChem Substance ID:
24900118
NACRES:
NA.77

biológiai forrás

synthetic

Minőségi szint

200

Teszt

≥96% (HPLC)

Forma

liquid

technika/technikák

HPLC: suitable

szín

faint brown to brown
 yellow to very dark yellow

oldhatóság

H2O: insoluble
acetone: miscible
chloroform: miscible
ethanol: miscible
vegetable oils: miscible

sűrűség

0.950 g/mL at 20 °C (lit.)

tárolási hőmérséklet

2-8°C

SMILES string

CC(C)CCCC(C)CCCC(C)CCCC1(C)CCc2c(C)c(O)c(C)c(C)c2O1

InChI

1S/C29H50O2/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8)19-17-26-25(7)27(30)23(5)24(6)28(26)31-29/h20-22,30H,9-19H2,1-8H3

Nemzetközi kémiai azonosító kulcs

GVJHHUAWPYXKBD-UHFFFAOYSA-N

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Alkalmazás

(±)-α-Tocopherol has been used for preparing mycobacterial emulsions. It has also been used to study its immunomodulatory effect on influenza virus.

Biokémiai/fiziológiai hatások

Tocopherols (vitamin E) comprise of a series (α, β, γ and δ) of chiral compounds that differ by the methylation degree of the phenol moiety of the chromanol ring. They function as lipid soluble antioxidants and protect cell membranes from oxidative damage. α-tocopherols are favorably absorbed by humans and their nicotinate salts can function as vitamin E supplements. Studies have also reported that vitamin E can prevent cell damage caused by pharmacologically induced epilepsy in rats.

Elkészítési megjegyzés

(±)-α-Tocopherol is miscible with chloroform, ethanol, ether, acetone, and vegetable oils. However, it is practically insoluble in water. (±)-α-Tocopherol is unstable under alkaline conditions.

Piktogramok

Exclamation mark
GHS07

Figyelmeztetés

Warning

Figyelmeztető mondatok

H317

Veszélyességi osztályok

Skin Sens. 1

Tárolási osztály kódja

10 - Combustible liquids

WGK

WGK 1

Egyéni védőeszköz

Eyeshields, Gloves

Válasszon a legfrissebb verziók közül:

Analitikai tanúsítványok (COA)

Lot/Batch Number
0000415404
0000415404
MKCX1479
0000370394
0000328494

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Dokumentumtár megtekintése

M Tagami et al.
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Thomas H Sanderson et al.
Molecular and cellular neurosciences, 64, 116-122 (2015-01-13)
Cellular mechanisms involved in multiple neurodegenerative diseases converge on mitochondria to induce overproduction of reactive oxygen species, damage to mitochondria, and subsequent cytochrome c release. Little is currently known regarding the contribution mitochondrial dynamics play in cytochrome c release following
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Ida Johansson et al.
Autophagy, 11(9), 1636-1651 (2015-08-04)
Accumulation and aggregation of misfolded proteins is a hallmark of several diseases collectively known as proteinopathies. Autophagy has a cytoprotective role in diseases associated with protein aggregates. Age-related macular degeneration (AMD) is the most common neurodegenerative eye disease that evokes
Marina G Yefimova et al.
Autophagy, 9(5), 653-666 (2013-02-27)
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