SAB5700418

Anti-Phospho-beta Catenin-S552 antibody produced in rabbit

• Szinonimák: CTNNB, CTNNB1, MRD19, armadillo, beta Catenin
• UNSPSC kód: 12352203
• NACRES: NA.41

Tulajdonságok

• biológiai forrás: rabbit
• Minőségi szint: 100
• antitest forma: affinity isolated antibody
• antitest terméktípus: primary antibodies
• klón: polyclonal
• form: buffered aqueous solution
• molekulatömeg: 85; 9
• faj reaktivitás: mouse, human, rat
• koncentráció: 1.48 mg/ml
• technika/technikák: western blot: 1:500-1:2000
• UniProt elérési szám: P35222
• kiszállítva: wet ice
• tárolási hőmérséklet: −20°C
• célzott transzláció utáni módosítás: phosphorylation (pSer552)
• Géninformáció: human ... CTNNB1(1499)

Leírás

Általános leírás

The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants.

Immunogen

A synthetic phosphorylated peptide around S552 of human beta Catenin (NP_001091679).

Fizikai forma

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Tárolás és stabilitás

Store at -20℃. Avoid freeze / thaw cycles.

Biztonsági adatok

• Tárolási osztály kódja: 12 - Non Combustible Liquids
• WGK: WGK 1
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable