SAB5700015

Anti-SMARCA4 antibody produced in rabbit

• Szinonimák: BAF190, BAF190A, BRG1, CSS4, MRD16, RTPS2, SMARCA4, SNF2, SNF2L4, SNF2LB, SWI2, hSNF2b
• UNSPSC kód: 12352203
• NACRES: NA.41

Tulajdonságok

• biológiai forrás: rabbit
• Minőségi szint: 100
• antitest forma: affinity isolated antibody
• antitest terméktípus: primary antibodies
• klón: polyclonal
• form: buffered aqueous solution
• molekulatömeg: 181; 184
• faj reaktivitás: human
• koncentráció: 2.97 mg/ml
• technika/technikák: immunofluorescence: 1:20-1:50; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:2000
• UniProt elérési szám: P51532
• kiszállítva: wet ice
• tárolási hőmérséklet: −20°C
• célzott transzláció utáni módosítás: unmodified
• Géninformáció: human ... SMARCA4(6597)

Leírás

Általános leírás

The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene.

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 30-130 of human SMARCA4 (NP_003063.2).

Fizikai forma

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Tárolás és stabilitás

Store at -20℃. Avoid freeze / thaw cycles.

Biztonsági adatok

• Tárolási osztály kódja: 12 - Non Combustible Liquids
• WGK: WGK 1
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable