SAB3500395

Anti-PDL-2 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• Szinonimák: PDL2 Antibody - Anti-PDL-2 antibody produced in rabbit, Pdl2 Antibody, Anti-B7DC, Anti-PD-L2, Anti-Programmed cell death 1 ligand-2, Anti-Programmed death ligand 1
• UNSPSC kód: 12352203
• NACRES: NA.41
• konjugátum: unconjugated
• application: ELISA (i); IF; IHC; WB
• klón: polyclonal
• faj reaktivitás: human, rat, mouse
• citations: 11
• technika/technikák: immunofluorescence: suitable; immunohistochemistry: suitable; indirect ELISA: suitable; western blot: suitable

Tulajdonságok

• biológiai forrás: rabbit
• Minőségi szint: 100
• konjugátum: unconjugated
• antitest forma: affinity isolated antibody
• antitest terméktípus: primary antibodies
• klón: polyclonal
• Forma: buffered aqueous solution
• molekulatömeg: predicted mol wt 30 kDa
• faj reaktivitás: human, rat, mouse
• technika/technikák: immunofluorescence: suitable; immunohistochemistry: suitable; indirect ELISA: suitable; western blot: suitable
• NCBI elérési szám: NP_079515
• UniProt elérési szám: Q9BQ51
• kiszállítva: dry ice
• tárolási hőmérséklet: −20°C
• célzott transzláció utáni módosítás: unmodified
• Géninformáció: human ... PDCD1LG2(80380)

Leírás

Általános leírás

Programmed cell death 1 ligand 2 (PD-L2 or PDCD1 ligand 2) is also known as butyrophilin B7-DC or CD273. It belongs to the immunoglobulin superfamily. The gene encoding PDL-2 is localized on human chromosome 9p24.1.

Immunogén

PDL-2 antibody was raised against a 16 amino acid peptide from near the center of human PDL-2.

Alkalmazás

Anti-PDL-2 antibody produced in rabbit has been used in immunohistochemistry.

Biokémiai/fiziológiai hatások

The expression of programmed cell death 1 ligand 2 (PD-L2) or CD antigen 273 (CD273) is up-regulated by interferon-γ (IFNG/IFN-γ) stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with colony-stimulating factor-2 (CSF2) and interleukin-4 (IL-4). PD-L2 is involved in the co-stimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PD-L2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.

Tulajdonságok és előnyök

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Kapcsolódás

The action of this antibody can be blocked using blocking peptide SBP3500395.

Fizikai forma

Supplied in PBS with 0.02% sodium azide.

Jogi nyilatkozat

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Biztonsági adatok

• Tárolási osztály kódja: 10 - Combustible liquids
• WGK: WGK 2
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable