R4528

Anti-hnRNP-A1 antibody, Mouse monoclonal

clone 9H10, purified from hybridoma cell culture

• Szinonimák: Anti-heterogeneous nuclear ribonucleoprotein-A1
• MDL-szám: MFCD06798702
• UNSPSC kód: 12352203
• NACRES: NA.41

Tulajdonságok

• biológiai forrás: mouse
• Minőségi szint: 200
• konjugátum: unconjugated
• antitest forma: purified immunoglobulin
• antitest terméktípus: primary antibodies
• klón: 9H10, monoclonal
• form: buffered aqueous solution
• molekulatömeg: antigen ~34 kDa
• faj reaktivitás: human, hamster, monkey, rat, bovine, mouse, canine
• technika/technikák: immunocytochemistry: suitable; immunohistochemistry: suitable; immunoprecipitation (IP): suitable; microarray: suitable; western blot: 0.5-1.0 μg/mL using total cell extract of 293T cells
• izotípus: IgG2b
• UniProt elérési szám: P09651
• kiszállítva: dry ice
• tárolási hőmérséklet: −20°C
• célzott transzláció utáni módosítás: unmodified
• Géninformáció: human ... HNRNPA1(3178) ; mouse ... Hnrnpa1(15382) ; rat ... Hnrnpa1(29578)

Leírás

Általános leírás

hnRNP-A1 (heterogeneous nuclear ribonucleoprotein) is a pre-mRNA/mRNA binding protein, that belongs to the hnRNP family. It is located in chromosome 12q13.1. It is located in the nucleoplasm but it travels between the nucleus and the cytoplasm. It has two RNP motif RNA-binding domains (RBDs) at the amino terminus and a glycine-rich domain at the carboxyl terminus.

Immunogen

purified human hnRNP-A1.

Alkalmazás

Anti-hnRNP-A1 has been used in immunofluorescence, immunohistochemistry and western blotting.

Does not immunoprecipitate the hnRNP complex.

Biokémiai/fiziológiai hatások

hnRNP-A1 (heterogeneous nuclear ribonucleoprotein) participates in several RNA metabolisms. It also participates in deep vein thrombosis patients with behçet′s disease. hnRNPA1 mutations results in amyotrophic lateral sclerosis and multisystem proteinopathy.

Fizikai forma

Solution in 0.01 M phosphate buffered saline, pH 7.4, and 15 mM sodium azide.

Jogi nyilatkozat

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Biztonsági adatok

• Tárolási osztály kódja: 12 - Non Combustible Liquids
• WGK: nwg
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable