PHG0001

HEPES

• Szinonimák: 4-(2-Hydroxyethyl)piperazine-1-ethanesulfonic acid, N-(2-Hydroxyethyl)piperazine-N′-(2-ethanesulfonic acid)
• Tapasztalati képlet (Hill-képlet): C₈H₁₈N₂O₄S
• CAS-szám: 7365-45-9
• Molekulatömeg: 238.30
• Beilstein: 883043
• EC-szám: 230-907-9
• MDL-szám: MFCD00006158
• UNSPSC kód: 12161700
• NACRES: NA.21

Tulajdonságok

• biológiai forrás: synthetic
• Minőségi szint: 400
• Forma: powder
• technika/technikák: cell culture | mammalian: suitable
• szennyeződések: Endotoxin, microbial, and trace metals; tested
• pH: 4.7-5.3 (, )
• hasznos pH-tartomány: 6.8-8.2
• pKa (25 °C): 7.5
• alkalmasság: suitable for manufacturing use
• idegen aktivitás: Cytotoxicity, DNase, NICKase, RNase, and Protease; tested
• SMILES string: OCCN1CCN(CC1)CCS(O)(=O)=O
• InChI: 1S/C8H18N2O4S/c11-7-5-9-1-3-10(4-2-9)6-8-15(12,13)14/h11H,1-8H2,(H,12,13,14)
• Nemzetközi kémiai azonosító kulcs: JKMHFZQWWAIEOD-UHFFFAOYSA-N

Leírás

Általános leírás

Our SAFC^® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Buffer quality is vital for the success of biopharmaceutical processes, because buffers are indispensable in nearly every production step.

Our broad portfolio of buffer materials manufactured under appropriate controls is tailored to your needs. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.

Alkalmazás

HEPES is a biological buffer often referred to as a “Good′s” buffer. It is the most commonly used biological buffer since the pKa of HEPES is 7.31 which corresponds to the physiological pH of 7.36. HEPES is considered to be non-toxic to culture cell lines, highly water soluble and provides high solution clarity.

HEPES is used in cell culture media, in biopharma buffer formulations (both upstream and downstream), and in diagnostic reagents. HEPES based buffers are used in purification bioprocesses of antibodies, bioactives, proteins and growth factors.

Jogi információk

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Biztonsági adatok

• Tárolási osztály kódja: 11 - Combustible Solids
• WGK: WGK 1
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable