Összes fotó(1)
Fontos dokumentumok
P8997
Anti-Purinergic Receptor P2X7 (extracellular)−FITC antibody produced in rabbit
affinity isolated antibody, lyophilized powder
Szinonimák:
Anti-P2Z
Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez
Összes fotó(1)
About This Item
konjugátum:
FITC conjugate
application:
FACS
klón:
polyclonal
faj reaktivitás:
human, rat, mouse
citations:
2
technika/technikák:
flow cytometry: 10 μg/test using Jurkat T-cells
Javasolt termékek
biológiai forrás
rabbit
Minőségi szint
konjugátum
FITC conjugate
antitest forma
affinity isolated antibody
antitest terméktípus
primary antibodies
klón
polyclonal
Forma
lyophilized powder
faj reaktivitás
human, rat, mouse
technika/technikák
flow cytometry: 10 μg/test using Jurkat T-cells
UniProt elérési szám
kiszállítva
dry ice
tárolási hőmérséklet
−20°C
célzott transzláció utáni módosítás
unmodified
Géninformáció
human ... P2RX7(5027)
mouse ... P2rx7(18439)
rat ... P2rx7(29665)
Related Categories
Általános leírás
Purinergic Receptor P2X7 is a ionotrophic ATP-gated channel responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. ATP activation of the P2RX7 leads to recruitment of pannexin pores which allow small molecules such as ATP to leak out of cells further activating of purinergic receptors and physiological responses such a spreading cytoplasmic waves of calcium.
Fluorescein isothiocyanate (FITC) is a fluorescein derivative (fluorochrome) used to tag antibodies, including secondary antibodies, for use in fluorescence-based assays and procedures. FITC excites at 495 nm and emits at 521 nm.
Fluorescein isothiocyanate (FITC) is a fluorescein derivative (fluorochrome) used to tag antibodies, including secondary antibodies, for use in fluorescence-based assays and procedures. FITC excites at 495 nm and emits at 521 nm.
Egyediség
Rabbit polyclonal anti-Purinergic Receptor P2X7 (extracellular)−FITC antibody reacts with rat, human, and mouse purinergic receptor P2X7 (extracellular).
Immunogén
synthetic peptide corresponding to residues 136-152 of mouse P2X7 receptor. Sequence homology with human, mouse, and rat is identical. Bovine is 14/17 residues identical.
Alkalmazás
Rabbit polyclonal anti-Purinergic Receptor P2X7 (extracellular)−FITC antibody is used to tag Purinergic Receptor P2X7 (extracellular) for detection and quantitation by fluorescence-based immunocytochemical and immunohistochemical (IHC) techniques. It is used as a probe to determine the presence and roles of Purinergic Receptor P2X7 (extracellular) in ATP-dependent processes such as cell lysis and calcium movement.
Fizikai forma
Lyophilized from phosphate buffered saline, pH 7.4, containing 1% BSA and 0.05% sodium azide.
Jogi nyilatkozat
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Tárolási osztály kódja
13 - Non Combustible Solids
WGK
WGK 2
Lobbanási pont (F)
Not applicable
Lobbanási pont (C)
Not applicable
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Jasmine M Manouchehri et al.
Frontiers in oncology, 12, 855032-855032 (2022-05-07)
Breast cancer affects two million patients worldwide every year and is the most common cause of cancer-related death among women. The triple-negative breast cancer (TNBC) sub-type is associated with an especially poor prognosis because currently available therapies fail to induce
Mingxuan Li et al.
Journal of immunology (Baltimore, Md. : 1950), 205(7), 1752-1762 (2020-09-02)
P2X7 receptor (P2X7R) is highly expressed on immune cells, triggering the release of cytokines and regulating autoimmune responses. To investigate P2X7R surface expression on T helper (Th) 1, Th17, and regulatory T (Treg) cells in patients with systemic lupus erythematosus
Tudóscsoportunk valamennyi kutatási területen rendelkezik tapasztalattal, beleértve az élettudományt, az anyagtudományt, a kémiai szintézist, a kromatográfiát, az analitikát és még sok más területet.
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