FLAAS

Adenosine 5′-triphosphate (ATP) disodium salt hydrate

vial of ~1 mg ATP

• Szinonimák: ATP disodium hydrate
• Lineáris képlet: C₁₀H₁₄N₅O₁₃P₃Na₂ · xH₂O
• CAS-szám: 34369-07-8
• Molekulatömeg: 551.14 (anhydrous basis)
• EC-szám: 213-579-1
• MDL-szám: MFCD00150755
• UNSPSC kód: 12352202
• eCl@ss: 32160414
• PubChem Substance ID: 24895005
• NACRES: NA.26

Tulajdonságok

• biológiai forrás: bacterial (Corynebacterium sp)
• Minőségi szint: 200
• Teszt: ≥90%
• Forma: lyophilized powder
• kiszerelés: vial of ~1 mg ATP
• tárolási hőmérséklet: −20°C
• SMILES string: Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O
• InChI: 1S/C10H16N5O13P3.2Na.H2O/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20;;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;;1H2/q;2*+1;/p-2/t4-,6-,7-,10-;;;/m1.../s1
• Nemzetközi kémiai azonosító kulcs: NTBQNWBHIXNPRU-MSQVLRTGSA-L

Leírás

Alkalmazás

Adenosine 5′-triphosphate (ATP) disodium salt hydrate has been:

• used as a standard to measure ATP by bioluminescence method
• used in kinase buffer to assess the interaction between death-associated protein kinases (DAPK2) and 14-3-3-β
• used as a standard in ATP colorimetric assay

Biokémiai/fiziológiai hatások

Adenosine 5′-triphosphate (ATP) is one of the nucleoside triphosphate present in living system. It controls various biologic processes such as glucose metabolism, muscle contraction and neurotransmission. Apart from this, ATP serves as an important energy source for the cell. Administration of ATP might be useful in the treatment of non-small-cell lung cancer.

Adenosine 5′-triphosphate was shown to have inhibitory effects on the inflammatory response by abrogating secretion of TNF-α and promoting secretion of Interleukin-10.

P₂ purinergic agonist; increases activity of Ca²⁺-activated K⁺ channels; substrate for ATP-dependent enzyme systems

Mennyiség

Each vial contains ~1.2 mg of Na₂ATP • 3H₂O equivalent to ~1.0 mg of ATP (2.0 μmol). Actual amount printed on the label.

Elkészítési megjegyzés

Prepared to be substantially vanadium-free.

Biztonsági adatok

• Tárolási osztály kódja: 11 - Combustible Solids
• WGK: WGK 2
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable
• Egyéni védőeszköz: Eyeshields, Gloves, type N95 (US)