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SIRNA

MISSION® siRNA Product Offerings

Custom and Predesigned siRNA

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Custom siRNA, High-throughput siRNA, Predesigned siRNA, siRNA, siRNA pools

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12352208

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MISSION® esiRNA targeting human SEMA3B

Sigma-Aldrich

EHU140161

MISSION® esiRNA

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MIRNA

MISSION® miRNA Product Offerings

MISSION® esiRNA targeting human FCGRT

Sigma-Aldrich

EHU076011

MISSION® esiRNA

Antonis C Antoniou et al.
The New England journal of medicine, 371(6), 497-506 (2014-08-08)
Germline loss-of-function mutations in PALB2 are known to confer a predisposition to breast cancer. However, the lifetime risk of breast cancer that is conferred by such mutations remains unknown. We analyzed the risk of breast cancer among 362 members of
Fuhui Xu et al.
PloS one, 9(9), e106509-e106509 (2014-09-04)
Improved drought tolerance is always a highly desired trait for agricultural plants. Significantly increased drought tolerance in Arabidopsis thaliana (Columbia-0) has been achieved in our work through the suppression of ESKMO1 (ESK1) gene expression with small-interfering RNA (siRNA) and overexpression
Chong He et al.
PLoS genetics, 10(12), e1004860-e1004860 (2014-12-19)
The common non-steroidal anti-inflammatory drug ibuprofen has been associated with a reduced risk of some age-related pathologies. However, a general pro-longevity role for ibuprofen and its mechanistic basis remains unclear. Here we show that ibuprofen increased the lifespan of Saccharomyces
Maria Dermit et al.
Developmental cell, 55(3), 298-313 (2020-11-11)
Translation of ribosomal protein-coding mRNAs (RP-mRNAs) constitutes a key step in ribosome biogenesis, but the mechanisms that modulate RP-mRNA translation in coordination with other cellular processes are poorly defined. Here, we show that subcellular localization of RP-mRNAs acts as a
Yanli Ma et al.
PloS one, 7(10), e47961-e47961 (2012-11-01)
Aflatoxin B1 (AFB1) is a potent carcinogen that can induce hepatocellular carcinoma. AFB1-8,9-exo-epoxide, one of AFB1 metabolites, acts as a mutagen to react with DNA and induce gene mutations, including the tumor suppressor p53. In addition, AFB1 reportedly stimulates IGF
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Regardless of next-generation sequencing (NGS) platform, universal and index adapter sequences are required for the proper assembly of sample fragments.

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Az újgenerációs szekvenálási (NGS) platformtól függetlenül univerzális és index adapterszekvenciákra van szükség a mintadarabok megfelelő összeállításához.

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Custom siRNA Duplex Plates

Use our synthetic, small interfering RNA (siRNA) duplex plates to identify gene function, elucidate pathways, and screen for potential new drug targets.

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LightCycler probes are highly sensitive and sequence-specific fluorescent probes designed for use with the Roche LightCycler instruments.

Easy Oligo

Easy Oligo is suitable for a wide range of applications including PCR , sequencing and real-time quantitative PCR (as a primer)

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As the world’s leading supplier of oligonucleotides, Sigma-Aldrich delivers the largest portfolio of expertise to its diagnostic partners. ISO 13485 & cGMP/ASR certified.

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