P7036

Parathyroid hormone human

≥92% (HPLC), powder

• Szinonimák: PTH, Parathormone
• Tapasztalati képlet (Hill-képlet): C₄₀₈H₆₇₄N₁₂₆O₁₂₆S₂
• CAS-szám: 68893-82-3
• Molekulatömeg: 9424.62
• MDL-szám: MFCD00081830
• UNSPSC kód: 51111800
• NACRES: NA.32
• Forma: powder
• Teszt: ≥92% (HPLC)

Tulajdonságok

• sterilitás: non-sterile
• Minőségi szint: 200
• Teszt: ≥92% (HPLC)
• Forma: powder
• összetétel: Peptide content, ≥70%
• oldhatóság: water: 1 mg/mL, clear, colorless
• UniProt elérési szám: P01270
• kiszállítva: ambient
• tárolási hőmérséklet: −20°C
• Géninformáció: human ... PTH(5741)

Leírás

Amino Acid Sequence

Ser-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe-Val-Ala-Leu-Gly-Ala-Pro-Leu-Ala-Pro-Arg-Asp-Ala-Gly-Ser-Gln-Arg-Pro-Arg-Lys-Lys-Glu-Asp-Asn-Val-Leu-Val-Glu-Ser-His-Glu-Lys-Ser-Leu-Gly-Glu-Ala-Asp-Lys-Ala-Asp-Val-Asn-Val-Leu-Thr-Lys-Ala-Lys-Ser-Gln

Általános leírás

Parathyroid hormone (PTH) is a circulating hormone secreted from the parathyroid gland. This hormone is synthesized as a pre-pro hormone. PTH is composed of binding regions that have a high affinity to a receptor and functional domains that interact with the receptors to initiate an intracellular signaling cascade.

Alkalmazás

Parathyroid hormone human has been used to incubate mature human adipocytes.

Biokémiai/fiziológiai hatások

Parathyroid hormone (PTH) exerts its effects on bone and kidney cells. This hormone plays a role in calcium homeostasis. PTH is secreted from the chief cells of the parathyroid gland in response to low extracellular calcium levels or higher levels of extracellular phosphate. PTH deficiency or excess PTH are associated with hypoparathyroidism and hyperparathyroidism, respectively.

Komponensek

Ser-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe-Val-Ala-Leu-Gly-Ala-Pro-Leu-Ala-Pro-Arg-Asp-Ala-Gly-Ser-Gln-Arg-Pro-Arg-Lys-Lys-Glu-Asp-Asn-Val-Leu-Val-Glu-Ser-His-Glu-Lys-Ser-Leu-Gly-Glu-Ala-Asp-Lys-Ala-Asp-Val-Asn-Val-Leu-Thr-Lys-Ala-Lys-Ser-Gln

Biztonsági adatok

• Tárolási osztály kódja: 11 - Combustible Solids
• WGK: WGK 3
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable