P3644

L-α-Phosphatidylcholine

from soybean, Type IV-S, ≥30% (enzymatic)

• Szinonimák: 1,2-Diacyl-sn-glycero-3-phosphocholine, 3-sn-Phosphatidylcholine, L-α-Lecithin, Azolectin, PC
• CAS-szám: 8002-43-5
• Beilstein: 5209585
• EC-szám: 232-307-2
• UNSPSC kód: 51321705
• NACRES: NA.25

Tulajdonságok

• biológiai forrás: soybean
• Minőségi szint: 200
• típus: Type IV-S
• Forma: solid
• koncentráció: ≥30% (enzymatic)
• oldhatóság: chloroform: soluble 100 mg/mL, clear to slightly hazy, yellow to orange
• funkcionális csoport: phospholipid
• lipidtípus: phosphoglycerides
• kiszállítva: ambient
• tárolási hőmérséklet: −20°C
• SMILES string: [P](=O)([O-])(OC[C@H](OC(=O)CCCCCCC\C=C/C\C=C/CCCCC)COC(=O)CCCCCCCCCCCCCCC)OCC[N+](C)(C)C
• InChI: 1S/C42H80NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h14,16,20-21,40H,6-13,15,17-19,22-39H2,1-5H3/b16-14-,21-20-/t40-/m1/s1
• Nemzetközi kémiai azonosító kulcs: JLPULHDHAOZNQI-ZTIMHPMXSA-N

Leírás

Alkalmazás

L-α-Phosphatidylcholine is suitable for use:

• as a component of human erythroid massive amplification culture (HEMA^def) medium for clinical expansion of human erythroblasts
• in the chloride efflux assay to examine the chloride permeability of lipid vesicles conferred by soluble CLIC1
• in an assay to measure solubilized wax synthase activity
• as a component of buffer A used for the resuspension of the cholate-solubilized catalytic unit of adenylate cyclase
• as a cryoprotectant for freezing ruminant sperm
• as a substrate for the estimation of phospholipase activity
• to make liposomes to assess their efficiency of recruitment of ARF (ADP ribosylation factor) and AP-1 (adaptor protein)
• in the preparation of the isolated catalytic unit of soluble adenylate cyclase

Biokémiai/fiziológiai hatások

Phosphatidylcholine is the major membrane phospholipid in eukaryotic cells, forming the structural component of these membranes. It also serves as a reservoir for several lipid messengers and a source for several bioactive lipids such as, lysophosphatidylcholine, phosphatidic acid, diacylglycerol, lysophosphatidylcholine, platelet activating factor, and arachidonic acid.

A major structural phospholipid in brain, comprising approx. 15% of total lipid; primarily localized to gray matter.

Elkészítési megjegyzés

Purified from P 5638

Biztonsági adatok

• Tárolási osztály kódja: 11 - Combustible Solids
• WGK: WGK 1
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable
• Egyéni védőeszköz: Eyeshields, Gloves, type N95 (US)