N1638

Nystatin Suspension

suspension, non-animal origin, suitable for cell culture, BioReagent

• Szinonimák: Fungicidin, Mycostatin
• CAS-szám: 1400-61-9
• UNSPSC kód: 12352207
• PubChem Substance ID: 24897511
• NACRES: NA.76

Tulajdonságok

• Terméknév: Nystatin Suspension, suspension, 10,000 unit/mL in DPBS, BioReagent, suitable for cell culture
• termékcsalád: BioReagent
• Minőségi szint: 200
• Forma: suspension
• koncentráció: 10,000 unit/mL in DPBS
• technika/technikák: cell culture | mammalian: suitable
• szennyeződések: endotoxin, tested
• szín: yellow
• antibiotikus hatásspektrum: fungi; yeast
• Hatásmechanizmus: cell membrane | interferes
• kiszállítva: dry ice
• tárolási hőmérséklet: −20°C
• SMILES string: C[C@@H]1OC(=O)C[C@H](O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@]2(O)C[C@H](O)[C@H]([C@H](C[C@@H](O[C@@H]3O[C@H](C)[C@@H](O)[C@H](N)[C@@H]3O)\C=C\C=C\C=C\C=C\CC\C=C\C=C\[C@H](C)[C@@H](O)[C@@H]1C)O2)C(O)=O
• InChI: 1S/C47H75NO17/c1-27-17-15-13-11-9-7-5-6-8-10-12-14-16-18-34(64-46-44(58)41(48)43(57)30(4)63-46)24-38-40(45(59)60)37(54)26-47(61,65-38)25-36(53)35(52)20-19-31(49)21-32(50)22-33(51)23-39(55)62-29(3)28(2)42(27)56/h5-6,8,10-18,27-38,40-44,46,49-54,56-58,61H,7,9,19-26,48H2,1-4H3,(H,59,60)/b6-5+,10-8+,13-11+,14-12+,17-15+,18-16+/t27-,28+,29-,30+,31+,32+,33+,34-,35+,36+,37-,38-,40+,41-,42+,43+,44-,46-,47+/m0/s1
• Nemzetközi kémiai azonosító kulcs: VQOXZBDYSJBXMA-QEKUPDCNSA-N

Leírás

Általános leírás

Chemical structure: polyene

Alkalmazás

Nystatin suspension has been used:

• to inhibit caveolin-mediated endocytosis
• as a component of Eagle′s minimum essential medium (EMEM)
• to enumerate lactic acid bacteria (LAB)
• in preventing cell culture contamination and inducing interleukin (IL)-1, IL-8, and tumor necrosis factor a secretion in toll-like receptor 2 (TLR2)-expressing THP1 cells.

This product is recommended for use in cell culture applications at 24 mL/L.

Biokémiai/fiziológiai hatások

Nystatin is a polyene, broad-spectrum antibiotic, which modifies the microstructure of lipid rafts. It can sequester cholesterol present on the cell membrane of eukaryotes. Nystatin regulates immune responses through cytokine signaling, lymphocyte activation and pathogen recognition.

Vigyázat

This product is stable at 37°C for three days.

Elkészítési megjegyzés

It is 0.1μ filtered and cell culture tested.

Egyéb megjegyzések

Nystatin suspension available in 20 mL and 100 mL pack size.
Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.

Biztonsági adatok

• Tárolási osztály kódja: 10 - Combustible liquids
• WGK: WGK 2
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable