L1882

Lectin from Triticum vulgaris (wheat)

agarose conjugate, saline suspension

• Szinonimák: WGA, Wheat germ agglutinin
• UNSPSC kód: 12352202
• NACRES: NA.32

Tulajdonságok

• konjugátum: agarose conjugate
• Minőségi szint: 200
• form: saline suspension
• a címkézés mértéke: 5-10 mg per mL
• matrix: cross-linked 4% beaded agarose
• mátrix aktiválás: cyanogen bromide
• kapacitás: ≥0.1 mg/mL binding capacity (ovomucoid)
• tárolási hőmérséklet: 2-8°C

Leírás

Általános leírás

Lectins are carbohydrate-binding proteins, found in fungi, plants and animals. The secondary structure of a lectin is rich in β-strands and possesses a carbohydrate binding sites on the surface.

Alkalmazás

Used for the purification of glycoproteins containing (D-N-acetylglucosamine)₂ or N-acetylneuraminic acid.

Biokémiai/fiziológiai hatások

Lectins are known to be useful in glycoconjugate characterizing, imaging and targeting. They specifically interact with oligosaccharides, glycoproteins and glycolipids. Hence, lectins are used in microarray assays, enabling efficient glycome profiling. In plants and fungi, lectins defend against pathogens or feeders. They are also involved in host recognition and tissue adhesion.

WGA is not blood group specific but has an affinity for N-acetyl-β-D-glucosaminyl residues and N-acetyl-β-D-glucosamine oligomers. WGA contains no protein-bound carbohydrate.

Fizikai forma

Suspension in 1.0 M NaCl containing 15 mM sodium azide

Elkészítési megjegyzés

Conjugates are prepared from affinity purified lectin.

Biztonsági adatok

• Tárolási osztály kódja: 10 - Combustible liquids
• WGK: WGK 3
• Egyéni védőeszköz: Eyeshields, Gloves