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Fontos dokumentumok
I2143
Anti-Interleukin-6 antibody produced in rabbit
IgG fraction of antiserum, buffered aqueous solution
Szinonimák:
Anti-IL-6
Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez
Összes fotó(1)
About This Item
konjugátum:
unconjugated
application:
Neutral
RIA
RIA
klón:
polyclonal
faj reaktivitás:
human
citations:
9
technika/technikák:
neutralization: suitable using human IL-6 in a T1165 cell proliferation bioassay
radioimmunoassay: suitable
radioimmunoassay: suitable
Javasolt termékek
biológiai forrás
rabbit
Minőségi szint
konjugátum
unconjugated
antitest forma
IgG fraction of antiserum
antitest terméktípus
primary antibodies
klón
polyclonal
Forma
buffered aqueous solution
faj reaktivitás
human
technika/technikák
neutralization: suitable using human IL-6 in a T1165 cell proliferation bioassay
radioimmunoassay: suitable
UniProt elérési szám
kiszállítva
dry ice
tárolási hőmérséklet
−20°C
célzott transzláció utáni módosítás
unmodified
Géninformáció
human ... IL6(3569)
Related Categories
Általános leírás
Anti-Interleukin 6 (IL-6) is produced in rabbit using purified human recombinant IL-6 produced in E. coli as the immunogen. Interleukin-6 is a multifunctional protein originally discovered in the media of cells stimulated with double stranded RNA. Interleukin-6 (IL-6) is a cytokine produced by activated T cells, endothelial cells, fibroblasts and activated monocytes or macrophages.
Egyediség
The antibody will neutralize the biological activity of human IL-6 in cell culture. The antibody does not cross-react with human IL-1β, TNF-α or mouse IL-6.
Immunogén
Purified human recombinant IL-6 produced in E. coli.
Alkalmazás
Anti-Interleukin-6 antibody can be used in western blotting and ELISA for studying human IL-6. It can also be used for dot blot immunoassay. Anti-Interleukin-6 antibody can be used for selective neutralization of human IL-6 bioactivity in cell culture. It can also be used in radioimmunoassay (RIA) (diluted 1:60,000).
It may also be used in immunoblotting.
Biokémiai/fiziológiai hatások
Interleukin 6 (IL-6) acts upon a variety of cells, including fibroblasts, myeloid progenitor cells, T cells, B cells, and hepatocytes. Interleukin 6 (IL-6) also potentiates the proliferative effect of Interleukin 3 (IL-3) on multipotential hematopoietic progenitors.
Interleukin-6 (IL-6) is a cytokine produced by activated T cells, endothelial cells, fibroblasts and activated monocytes or macrophages. It plays a crucial role in regulating the acute phase response as well as responses occurs after injury and infection. It interacts with IL-2 and facilitates in the proliferation of T lymphocytes.
Fizikai forma
Solution, 0.2 μm filtered, in 0.5 mL phosphate buffered saline, pH 7.4.
Jogi nyilatkozat
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Tárolási osztály kódja
10 - Combustible liquids
WGK
WGK 3
Lobbanási pont (F)
Not applicable
Lobbanási pont (C)
Not applicable
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Az ügyfelek ezeket is megtekintették
Inflammation, obesity, stress and coronary heart disease: is interleukin-6 the link?
Yudkin J S, et al.
Atherosclerosis, 148(2), 209-214 (2000)
Vuong Cat Khanh et al.
Stem cells and development, 29(21), 1382-1394 (2020-09-10)
Cancer metastasis is the leading cause of mortality among breast cancer patients. Type 2 diabetes mellitus (T2DM) has been suggested as a risk factor of breast cancer; however, whether or not T2DM is associated with breast tumor metastasis remains unclear.
Debra J Romberger et al.
American journal of physiology. Lung cellular and molecular physiology, 311(1), L101-L110 (2016-05-18)
Agricultural dust exposure results in significant lung inflammation, and individuals working in concentrated animal feeding operations (CAFOs) are at risk for chronic airway inflammatory diseases. Exposure of bronchial epithelial cells to aqueous extracts of hog CAFO dusts (HDE) leads to
Interleukin-6 and chronic inflammation
Gabay C, et al.
Arthritis Research & Therapy, 8(2), S3-S3 (2006)
A crosstalk between myeloma cells and marrow stromal cells stimulates production of DKK1 and interleukin-6: A potential role in the development of lytic bone disease and tumor progression in multiple myeloma
Gunn W G, et al.
Stem Cells, 24(4), 986-991 (2006)
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