E2250

Ellagic acid

≥95% (HPLC), powder, from tree bark

• Szinonimák: 4,4′,5,5′,6,6′-Hexahydroxydiphenic acid 2,6,2′,6′-dilactone, Alizarin Yellow, Benzoaric acid, Elagostasine, Eleagic acid, Gallogen, Lagistase
• Tapasztalati képlet (Hill-képlet): C₁₄H₆O₈
• CAS-szám: 476-66-4
• Molekulatömeg: 302.19
• Beilstein: 47549
• EC-szám: 207-508-3
• MDL-szám: MFCD00006914
• UNSPSC kód: 12352205
• PubChem Substance ID: 24894460
• NACRES: NA.77

Tulajdonságok

• biológiai forrás: tree bark
• Minőségi szint: 200
• Teszt: ≥95% (HPLC)
• Forma: powder
• eltarthatósági idő: 5 yr
• oldhatóság: 1 M NaOH: 10 mg/mL
• alkalmazás(ok): metabolomics; vitamins, nutraceuticals, and natural products
• SMILES string: Oc1cc2C(=O)Oc3c(O)c(O)cc4C(=O)Oc(c1O)c2-c34
• InChI: 1S/C14H6O8/c15-5-1-3-7-8-4(14(20)22-11(7)9(5)17)2-6(16)10(18)12(8)21-13(3)19/h1-2,15-18H
• Nemzetközi kémiai azonosító kulcs: AFSDNFLWKVMVRB-UHFFFAOYSA-N
• Géninformáció: human ... CSK(1445) , DYRK1A(1859) , GSK3B(2932) , SRC(6714) ; rat ... Lyn(81515) , Syk(25155)

Leírás

Általános leírás

Ellagic acid is a naturally occurring phenolic acid in many fruits and vegetables, as a secondary plant metabolite. It is commonly found in green tea, pomegranate, strawberries, blackberries, raspberries, and walnuts.

Alkalmazás

Ellagic acid has been used:

• to study the metabolism of dietary phenolic acids by Lactobacillus plantarum CECT 748T
• as a potential substrate for the high production of Lactobacillus plantarum tannase
• as a standard in the study to examine the phenolic components and anti-oxidant activity of nettle
• to study the links between dietary ellagic acid and epigenetic modulation of adipogenesis

Biokémiai/fiziológiai hatások

Ellagic acid has been found to exhibit antioxidant activity by virtue of having an inhibitory effect on the oxidation of low-density lipoproteins. This makes them have a cardioprotective effect on humans. In addition, it shows anticarcinogenic, antifibrotic, antiplasmodial, apoptotic, and chemopreventive activities as well.

Commonly occurring plant polyphenol, inhibitor of glutathione S-transferase. Used for the assay of factor XIIa in plasma. Contact activation in blood coagulation.

Biztonsági adatok

• Tárolási osztály kódja: 11 - Combustible Solids
• WGK: WGK 1
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable
• Egyéni védőeszköz: dust mask type N95 (US), Eyeshields, Gloves