C9538

Coenzyme Q₁₀

≥98% (HPLC), powder, antioxidant

• Szinonimák: CoQ10, Q-10, Ubiquinone 50, Ubiquinone-10
• Tapasztalati képlet (Hill-képlet): C₅₉H₉₀O₄
• CAS-szám: 303-98-0
• Molekulatömeg: 863.34
• Beilstein: 1900141
• EC-szám: 206-147-9
• MDL-szám: MFCD00042919
• UNSPSC kód: 12352200
• PubChem Substance ID: 24893170
• NACRES: NA.77

Tulajdonságok

• Terméknév: Coenzyme Q₁₀, ≥98% (HPLC)
• Minőségi szint: 200
• Teszt: ≥98% (HPLC)
• Forma: powder
• szín: yellow to dark orange
• mp: 49 °C
• alkalmazás(ok): cell analysis
• tárolási hőmérséklet: −20°C
• SMILES string: O=C(C(OC)=C1OC)C(C/C=C(C)/CC/C=C(CC/C=C(CC/C=C(CC/C=C(CC/C=C(CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CCC=C(C)C)\C)\C)\C)\C)\C)=C(C)C1=O
• InChI: 1S/C59H90O4/c1-44(2)24-15-25-45(3)26-16-27-46(4)28-17-29-47(5)30-18-31-48(6)32-19-33-49(7)34-20-35-50(8)36-21-37-51(9)38-22-39-52(10)40-23-41-53(11)42-43-55-54(12)56(60)58(62-13)59(63-14)57(55)61/h24,26,28,30,32,34,36,38,40,42H,15-23,25,27,29,31,33,35,37,39,41,43H2,1-14H3/b45-26+,46-28+,47-30+,48-32+,49-34+,50-36+,51-38+,52-40+,53-42+
• Nemzetközi kémiai azonosító kulcs: ACTIUHUUMQJHFO-UPTCCGCDSA-N

Leírás

Általános leírás

Coenzyme Q (CoQ), also known as ubiquinone, is a lipid-soluble antioxidant and is an essential component of the mitochondrial electron transport chain. The molecule contains a biologically active quinone with a benzoquinone ring and an isoprenoid sidechain. Q10 is synthesized in the cytoplasm and mitochondria () which generates ATP through aerobic cellular respiration. CoQ10 is required for the optimal functioning of the immune system and for cardiovascular health (). The ability to repress inflammatory gene expression exhibits its anti-inflammatory property ( ) Genetic failure or ageing results in CoQ10 deficiency, indicated by suppression of immune function. ()

Alkalmazás

Coenzyme Q10 (CoQ10) has been used:

• as a bioactive compound to study its immune modulating properties in vitro
• as a standard for high-performance liquid chromatography
• to study its effect on exercised rat aorta
• in the cellular CoQ uptake assay

Biokémiai/fiziológiai hatások

Coenzyme Q10 is an endogenous cellular antioxidant and an essential component of the electron transfer chain. CoQ10 takes part in aerobic cellular respiration and generation of energy in the form of ATP.

Biztonsági adatok

• Tárolási osztály kódja: 11 - Combustible Solids
• WGK: WGK 3
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable
• Egyéni védőeszköz: Eyeshields, Gloves, type N95 (US)