C6895

Cefaclor

• Szinonimák: 7-(D-2-Amino-2-phenylacetamido)-3-chloro-3-cephem-4-carboxylic acid
• Tapasztalati képlet (Hill-képlet): C₁₅H₁₄ClN₃O₄S
• CAS-szám: 53994-73-3
• Molekulatömeg: 367.81
• Beilstein: 8176092
• EC-szám: 258-909-5
• MDL-szám: MFCD00151471
• UNSPSC kód: 51283701
• PubChem Substance ID: 24278331
• NACRES: NA.85

Tulajdonságok

• Forma: powder or crystals
• Minőségi szint: 200
• oldhatóság: soluble (slightly soluble in water, practically insoluble in methanol, ethanol)
• antibiotikus hatásspektrum: Gram-negative bacteria; Gram-positive bacteria
• Hatásmechanizmus: cell wall synthesis | interferes
• SMILES string: N[C@@H](C(=O)N[C@H]1[C@H]2SCC(Cl)=C(N2C1=O)C(O)=O)c3ccccc3
• InChI: 1S/C15H14ClN3O4S/c16-8-6-24-14-10(13(21)19(14)11(8)15(22)23)18-12(20)9(17)7-4-2-1-3-5-7/h1-5,9-10,14H,6,17H2,(H,18,20)(H,22,23)/t9-,10-,14-/m1/s1
• Nemzetközi kémiai azonosító kulcs: QYIYFLOTGYLRGG-GPCCPHFNSA-N

Leírás

Általános leírás

Chemical structure: ß-lactam

Alkalmazás

Cefaclor has been used in the heterologous expression of AaOr7 and AaOr8 in Xenopus laevis oocytes. It has also been used in cultures of isolated trigeminal ganglion (TG) and dorsal root ganglion (DRG) neurons.

Cefaclor is used to study urinary tract, intra-abdominal, and Haemophilus influenzae infections . It is used to study the mechanism of human renal organic anion and peptide transporters such as hOAT1, hPEPT1, and hPEPT2 and to study the effects of inhibition of penicillin-binding proteins on bacterial cell wall mucopeptide synthesis .

Biokémiai/fiziológiai hatások

Cefaclor is a second generation cephalosporin with broad spectrum activity against Gram-negative and Gram-positive bacteria. It binds to penicillin-binding proteins and thereby inhibits the cell wall synthesis causing cell death.

Egyéb megjegyzések

Keep container tightly closed in a dry and well-ventilated place. Slightly soluble in water, practically insoluble in methanol, chloroform and benzene.

Biztonsági adatok

• Tárolási osztály kódja: 11 - Combustible Solids
• WGK: WGK 2
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable
• Egyéni védőeszköz: dust mask type N95 (US), Eyeshields, Faceshields, Gloves