F6377

Fluorescein sodium salt

Powder

• Szinonimák: Acid Yellow 73, D&C;Yellow No. 8, NaFl, NaFluo, Sodium fluorescein, Uranine
• Tapasztalati képlet (Hill-képlet): C₂₀H₁₀Na₂O₅
• CAS-szám: 518-47-8
• Molekulatömeg: 376.27
• Colour Index szám: 45350
• Beilstein: 3833041
• EC-szám: 208-253-0
• MDL-szám: MFCD00167039
• UNSPSC kód: 12171500
• PubChem Substance ID: 24894907
• NACRES: NA.47

Tulajdonságok

• Terméknév: Fluorescein sodium salt, used as fluorescent tracer
• Minőségi szint: 200
• Forma: powder
• technika/technikák: titration: suitable
• szín: orange to brown
• pH: 8.3 (20 °C, 10 g/L)
• mp: >300 °C
• oldhatóság: H₂O: 1 mg/mL
• sűrűség: 0.78 g/cm³ at 29.6 °C (85.3 °F at 699.7 hPa)
• fluoreszcencia: λ_ex 460 nm; λ_em 515 nm(lit.)
• alkalmazás(ok): diagnostic assay manufacturing; hematology; histology
• tárolási hőmérséklet: room temp
• SMILES string: [Na+].[Na+].[O-]c1ccc2c(Oc3cc([O-])ccc3C24OC(=O)c5ccccc45)c1
• InChI: 1S/C20H12O5.2Na/c21-11-5-7-15-17(9-11)24-18-10-12(22)6-8-16(18)20(15)14-4-2-1-3-13(14)19(23)25-20;;/h1-10,21-22H;;/q;2*+1/p-2
• Nemzetközi kémiai azonosító kulcs: RGPLGPBQJOQFJS-UHFFFAOYSA-L

Leírás

Általános leírás

Fluorescein is a xanthene dye and is a common labeling agent in biology.

Alkalmazás

Fluorescein sodium salt has been used as a solute to study microvessel permeability. It has been used as a test molecule to study blood barrier penetration.

Water soluble fluorescent dye used in permeability and vascular perfusion studies due to its small molecular radius. Sodium fluorescein is used as a fluorescent tracer to study blood-brain barrier (BBB) and blood-spinal cord barrier (BSCB) permeability in rodent models. The dye was used as a probe substrate in the study of organic anion transporting polypeptide (OATP) mediated drug transport in hepatocytes. Sodium fluorescein was also used to monitor in situ solute transportation into bone through fluorescence recovery after photobleaching (FRAP).

Biztonsági adatok

• Tárolási osztály kódja: 11 - Combustible Solids
• WGK: WGK 1
• Lobbanási pont (F): 423.7 °F - Pensky-Martens closed cup
• Lobbanási pont (C): 217.6 °C - Pensky-Martens closed cup
• Egyéni védőeszköz: Eyeshields, Gloves, type N95 (US)