D6750

Sodium deoxycholate

≥97% (titration)

• Szinonimák: 3α,12α-Dihydroxy-5β-cholanic acid sodium salt, 7-Deoxycholic acid sodium salt, Desoxycholic acid sodium salt
• Tapasztalati képlet (Hill-képlet): C₂₄H₃₉NaO₄
• CAS-szám: 302-95-4
• Molekulatömeg: 414.55
• Beilstein: 3581950
• EC-szám: 206-132-7
• MDL-szám: MFCD00064139
• UNSPSC kód: 12161900
• PubChem Substance ID: 24894044
• NACRES: NA.21

Tulajdonságok

• leírás: anionic
• Minőségi szint: 200
• Teszt: ≥97% (titration)
• form: powder
• molekulatömeg: micellar avg mol wt 1200-5000
• aggregált szám: 3-12
• CMC: 2-6 mM (20-25°C)
• oldhatóság: water: 50 mg/mL, clear, colorless to light yellow
• HLB (hidrofil/lipofil egyensúly): 16
• funkcionális csoport: carboxylic acid
• kiszállítva: ambient
• tárolási hőmérséklet: room temp
• SMILES string: [Na+].[H][C@]12CC[C@@]3([H])[C@]4([H])CC[C@H]([C@H](C)CCC([O-])=O)[C@@]4(C)[C@@H](O)C[C@]3([H])[C@@]1(C)CC[C@@H](O)C2
• InChI: 1S/C24H40O4.Na/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3;/h14-21,25-26H,4-13H2,1-3H3,(H,27,28);/q;+1/p-1/t14-,15-,16-,17+,18-,19+,20+,21+,23+,24-;/m1./s1
• Nemzetközi kémiai azonosító kulcs: FHHPUSMSKHSNKW-SMOYURAASA-M

Leírás

Általános leírás

Deoxycholic acid sodium salt, also known as Sodium Deoxycholate, is a highly versatile ionic detergent utilized for its exceptional ability to solubilize membrane-bound proteins and lyse cells. Its mechanism involves disrupting cell membranes and dissolving hydrophobic molecules, making it an invaluable reagent in scientific research applications. In protein research, it plays a pivotal role in solubilizing proteins, particularly those embedded in membranes, enabling their extraction, purification, and subsequent analysis.

Moreover, Sodium Deoxycholate extends its utility to nucleic acid extraction from cells and tissues. By lysing cells and disrupting cellular structures, it facilitates the release and purification of nucleic acids, proving valuable in cell biology and biochemical research. Beyond these applications, its effectiveness in cell lysis processes positions it as a valuable tool for breaking down cells and releasing their contents, finding applications in diverse biological studies, encompassing microscopy, cell biology, and biochemical research.

Alkalmazás

Sodium deoxycholate has been used in the lysis buffer prepared for brown adipose tissue. It has been used in the decellularization of aortic valvular conduit.

Biokémiai/fiziológiai hatások

Solubilizes fats for absorption in the intestines.

Tulajdonságok és előnyök

Highly versatile surfactant for your cell biology and biochemical research

Egyéb megjegyzések

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Biztonsági adatok

• Piktogramok: GHS07
• Figyelmeztetés: Warning
• Figyelmeztető mondatok: H302
• Óvintézkedésre vonatkozó mondatok: P264 - P270 - P301 + P312 - P501
• Veszélyességi osztályok: Acute Tox. 4 Oral
• Tárolási osztály kódja: 11 - Combustible Solids
• WGK: WGK 1
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable
• Egyéni védőeszköz: dust mask type N95 (US), Eyeshields, Gloves