BP787

Colecalciferol

British Pharmacopoeia (BP) Reference Standard

• Szinonimák: Cholecalciferol, (+)-Vitamin D₃, 7-Dehydrocholesterol activated, Activated 7-dehydrocholesterol, Calciol
• Tapasztalati képlet (Hill-képlet): C₂₇H₄₄O
• CAS-szám: 67-97-0
• Molekulatömeg: 384.64
• Beilstein: 2339331
• EC-szám: 200-673-2
• MDL-szám: MFCD00078131
• UNSPSC kód: 41116107
• NACRES: NA.24

Tulajdonságok

• grade: pharmaceutical primary standard
• API-család: colecalciferol
• form: crystalline
• eltarthatósági idő: limited shelf life, expiry date on the label
• gyártó/kereskedő neve: BP
• szín: white
• mp: 83-86 °C (lit.)
• alkalmazás(ok): pharmaceutical; pharmaceutical small molecule
• format: neat
• tárolási hőmérséklet: −20°C
• SMILES string: CC(C)CCC[C@@H](C)[C@@]1([H])CC[C@@]([C@]1(C)CCC/2)([H])C2=C\C=C(C[C@@H](O)CC3)/C3=C
• InChI: 1S/C27H44O/c1-19(2)8-6-9-21(4)25-15-16-26-22(10-7-17-27(25,26)5)12-13-23-18-24(28)14-11-20(23)3/h12-13,19,21,24-26,28H,3,6-11,14-18H2,1-2,4-5H3/b22-12+,23-13-/t21-,24+,25-,26+,27-/m1/s1
• Nemzetközi kémiai azonosító kulcs: QYSXJUFSXHHAJI-YRZJJWOYSA-N
• Géninformáció: human ... VDR(7421)

Leírás

Általános leírás

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Colecalciferol is a fat soluble vitamin, which participates in the calcium and phosphate metabolism. It is sourced either through the diet or by exposing skin to ultraviolet rays. Oral administration of vitamin D₃ is readily absorbed and is stored in adipose tissue.

Alkalmazás

Colecalciferol BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:

Alendronic Acid and Colecalciferol Tablets

Colecalciferol Injection

Paediatric Vitamins A, C and D Oral Drops

Colecalciferol Tablets

Calcium and Colecalciferol Chewable Tablets

Calcium and Ergocalciferol Tablets

Calcium and Ergocalciferol Chewable Tablets

Ergocalciferol Tablets

Calcium and Colecalciferol Tablets

Biokémiai/fiziológiai hatások

Vitamin D acts through a receptor that is a member of the ligand-dependent transcription factor superfamily. Modulates the proliferation and differentiation of both normal and cancer cells. Has antiproliferative and antimetastatic effects on breast, colon, and prostate cancer cells. Activated vitamin D receptors in intestine and bone maintain calcium absorbance and homeostasis.

Kiszerelés

Unit quantity: 500 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

Egyéb megjegyzések

Sales restrictions may apply.

Biztonsági adatok

• Piktogramok: GHS06,GHS08
• Figyelmeztetés: Danger
• Figyelmeztető mondatok: H300 + H310 + H330,H372
• Óvintézkedésre vonatkozó mondatok: P260 - P262 - P280 - P302 + P352 + P310 - P304 + P340 + P310 - P314
• Veszélyességi osztályok: Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - STOT RE 1 Oral
• Tárolási osztály kódja: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 2
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable