MABE144

Anti-Ago3 Antibody, clone 4B1-F6

clone 4B1-F6, from mouse

• Szinonimák: eIF-2C 3, eIF2C 3, FLJ12765, MGC86946
• UNSPSC kód: 12352203
• eCl@ss: 32160702
• NACRES: NA.41
• klón: 4B1-F6, monoclonal
• application: ICC; IP
• faj reaktivitás: human
• technika/technikák: immunocytochemistry: suitable; immunoprecipitation (IP): suitable

Tulajdonságok

• biológiai forrás: mouse
• Minőségi szint: 100
• antitest forma: purified immunoglobulin
• antitest terméktípus: primary antibodies
• klón: 4B1-F6, monoclonal
• faj reaktivitás: human
• technika/technikák: immunocytochemistry: suitable; immunoprecipitation (IP): suitable
• izotípus: IgG2aκ
• NCBI elérési szám: NP_079128
• UniProt elérési szám: Q9H9G7
• kiszállítva: wet ice
• célzott transzláció utáni módosítás: unmodified
• Géninformáció: human ... AGO3(192669)

Leírás

Általános leírás

Eukaryotic translation initiation factor 2C 3, Ago3, belongs to the argonaute family and contains 1 PAZ and 1 Piwi domain.

Ago3 is indicated to play a role in the RNA interference (RNAi) pathway, which is important for heterochromatin formation and accurate chromosome segregation. Unlike Ago1 and Ago2, Ago3 and AG04 do not possess the ability to dissociate miRNA duplexes in a minimal in vitro system. Re-introduction of any Ago variant into embyronic (ES) cells deficient for expression of all four Ago variants will rescue miRNA silencing defects and reduce apoptosis.

Immunogén

Recombinant protein corresponding to human Ago3.

Alkalmazás

Anti-Ago3 Antibody, clone 4B1-F6 is a Mouse Monoclonal Antibody for detection of Ago3 also known as eIF-2C 3, eIF2C 3, FLJ12765, MGC86946 & has been validated in ICC & IP.

Immunoprecipitation Analysis: A representative lot was used by an independent laboratory in HeLa cells. (Azuma-Mukai, A., et al. (2008). Proc Natl Acad Sci. USA. 105(23):7964-7969.)

Minőség

Evaluated by Immunocytochemistry in HeLa cells.

Immunocytochemistry Analysis: A 1:500 dilution of this antibody detected Ago3 in HeLa cells.

Cél megnevezése

96 kDa calculated.

Fizikai forma

Format: Purified

Egyéb megjegyzések

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Biztonsági adatok

• Tárolási osztály kódja: 12 - Non Combustible Liquids
• WGK: WGK 1
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable