GF307
β-NGF Protein, Human Recombinant Animal Free
The Nerve Growth Factor is a well characterized neurotropic protein that plays a critical role in the development of sympathetic & some sensory neurons in the peripheral nervous system. Manufactured using all non-animal reagents.
Szinonimák:
Nerve Growth Factor, NGF, BNGF, Beta NGF
Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez
Összes fotó(1)
About This Item
UNSPSC kód:
12352202
eCl@ss:
32160405
NACRES:
NA.77
Javasolt termékek
Minőségi szint
Teszt
>98% (SDS-PAGE and HPLC)
szennyeződések
<0.1 μg/mg protein endotoxin (<1EU/μg)
NCBI elérési szám
UniProt elérési szám
kiszállítva
dry ice
Általános leírás
Nerve Growth Factor (β-NGF) is a well characterized neurotropic protein that plays a critical role in the development of sympathetic and some sensory neurons in the peripheral nervous system. In addition, NGF can also act in the central nervous system as a trophic factor for basal forebrain cholinergic neurons. NGF has also been shown to have biological effects on nonneuronal tissues. β-NGF is a neurotrophic factor structurally related to BDNF, NT-3 and NT-4. β-NGF is a potent neurotrophic factor that signals through its receptor β-NGFR, and plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems. β-NGF also acts as a growth and differentiation factor for B lymphocytes and enhances B-cell survival. The functional form of human β-NGF is a noncovalently disulfide-linked homodimer, of two 13.5 kDa polypeptide monomers (238 total amino acid residues). The three disulfide bonds are required for biological activity.
Product Source: E. coli
Egyediség
Cross Reactivty
Chicken, Hamster, Mouse, Rat
Chicken, Hamster, Mouse, Rat
Alkalmazás
Research Category
Neuroscience
Neuroscience
Research Sub Category
Growth Factors & Receptors
Growth Factors & Receptors
Minőség
Bioactivity assay: Assay 1: Determined by the dose-dependent stimulation of the proliferation of human TF-1 cells. The expected ED50 is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 106 units/mg.
Assay 2: Determined by its ability to stimulate chick E9 DRG neurite outgrowth. The expected ED50 is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 106 units/mg.
Assay 2: Determined by its ability to stimulate chick E9 DRG neurite outgrowth. The expected ED50 is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 106 units/mg.
Fizikai forma
Product is filtered through a 0.2 micron filter before lyophilization.
Recombinant animal free human β-NGF is manufactured using all non-animal reagents
Tárolás és stabilitás
Store at -20°C for up to 6 months from date of receipt.
Jogi nyilatkozat
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Tárolási osztály kódja
11 - Combustible Solids
WGK
WGK 1
Lobbanási pont (F)
Not applicable
Lobbanási pont (C)
Not applicable
Analitikai tanúsítványok (COA)
Analitikai tanúsítványok (COA) keresése a termék sarzs-/tételszámának megadásával. A sarzs- és tételszámok a termék címkéjén találhatók, a „Lot” vagy „Batch” szavak után.
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