ABC20
Anti-Cystatin-C Antibody
from rabbit, purified by affinity chromatography
Szinonimák:
Cystatin-C, Cystatin-3, Gamma-trace, Neuroendocrine basic polypeptide, Post-gamma-globulin
Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez
Összes fotó(2)
About This Item
UNSPSC kód:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Javasolt termékek
biológiai forrás
rabbit
Minőségi szint
antitest forma
affinity isolated antibody
klón
polyclonal
tisztítva
affinity chromatography
faj reaktivitás
mouse, human, rat
technika/technikák
immunohistochemistry: suitable (paraffin)
western blot: suitable
NCBI elérési szám
UniProt elérési szám
kiszállítva
wet ice
célzott transzláció utáni módosítás
unmodified
Általános leírás
Cystatin-C is a cysteine protease inhibitor in mammals, which is essential in protein degradation and keeping an equilibrium between inhibitors and proteases. It is thought to be a better marker for renal dysfunction and potential kidney injury than creatinine. Recently, Cystatin-C has been implicated in primary hypertension and may be a novel marker in patients. Cystatin-C has also been implicated in oxidative stress-induced apoptosis of CNS neurons and has been shown to inhibit amyloid-beta deposition in Alzheimer′s disease models.
Immunogén
KLH-conjugated linear peptide corresponding to human Cystatin-C.
Alkalmazás
Anti-Cystatin-C Antibody detects level of Cystatin-C & has been published & validated for use in WB, IH(P).
Immunohistochemistry (paraffin) Analysis: A 1:1000 dilution of a previous lot detected Cystatin-C in purkinje cells of normal rat cerebellum, neurons of normal rat frontal lobe, and neurons in normal rat midbrain.
Research Category
Apoptosis & Cancer
Apoptosis & Cancer
Research Sub Category
Apoptosis - Additional
Neurodegenerative Diseases
Apoptosis - Additional
Neurodegenerative Diseases
Minőség
Evaluated by Western Blot in human kidney tissue lysate.
Western Blot Analysis: 0.5 µg/mL of this antibody detected Cystatin-C in 10 µg of human kidney tissue lysate.
Western Blot Analysis: 0.5 µg/mL of this antibody detected Cystatin-C in 10 µg of human kidney tissue lysate.
Cél megnevezése
~14 kDa observed.
An uncharacterized band may appear at ~62 kDa in some lysates.
An uncharacterized band may appear at ~62 kDa in some lysates.
Fizikai forma
Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Tárolás és stabilitás
Stable for 1 year at 2-8°C from date of receipt.
Analízis megjegyzés
Control
Human kidney tissue lysate
Human kidney tissue lysate
Egyéb megjegyzések
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Jogi nyilatkozat
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Tárolási osztály kódja
12 - Non Combustible Liquids
WGK
WGK 1
Lobbanási pont (F)
Not applicable
Lobbanási pont (C)
Not applicable
Analitikai tanúsítványok (COA)
Analitikai tanúsítványok (COA) keresése a termék sarzs-/tételszámának megadásával. A sarzs- és tételszámok a termék címkéjén találhatók, a „Lot” vagy „Batch” szavak után.
Már rendelkezik ezzel a termékkel?
Az Ön által nemrégiben megvásárolt termékekre vonatkozó dokumentumokat a Dokumentumtárban találja.
Aintzane Urbizu et al.
Neuropathology and applied neurobiology, 41(4), 507-519 (2014-03-13)
As cystatin C (CysC) is involved in some forms of neurodegeneration, we investigated the possible relationship between CysC and multiple system atrophy (MSA), including its parkinsonian (MSAp) and cerebellar (MSAc) phenotypes. Cystatin C gene (CST3) haplotypes were determined by PCR
Conformational specificity of the C4F6 SOD1 antibody; low frequency of reactivity in sporadic ALS cases.
Ayers, JI; Xu, G; Pletnikova, O; Troncoso, JC; Hart, PJ; Borchelt, DR
Acta Neuropathologica Communications null
David Pires et al.
Frontiers in immunology, 12, 742822-742822 (2021-12-07)
Tuberculosis owes its resurgence as a major global health threat mostly to the emergence of drug resistance and coinfection with HIV. The synergy between HIV and Mycobacterium tuberculosis (Mtb) modifies the host immune environment to enhance both viral and bacterial
Neus Barranco et al.
Translational neurodegeneration, 10(1), 37-37 (2021-09-28)
New fluid biomarkers for Alzheimer's disease (AD) that reveal synaptic and neural network dysfunctions are needed for clinical practice and therapeutic trial design. Dense core vesicle (DCV) cargos are promising cerebrospinal fluid (CSF) indicators of synaptic failure in AD patients.
April Nettesheim et al.
Journal of clinical medicine, 10(1) (2021-01-01)
Extracellular matrix (ECM) deposition in the trabecular meshwork (TM) is one of the hallmarks of glaucoma, a group of human diseases and leading cause of permanent blindness. The molecular mechanisms underlying ECM deposition in the glaucomatous TM are not known
Tudóscsoportunk valamennyi kutatási területen rendelkezik tapasztalattal, beleértve az élettudományt, az anyagtudományt, a kémiai szintézist, a kromatográfiát, az analitikát és még sok más területet.
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