AB1286-I
Anti-Monocarboxylate Transporter 1 Antibody
from chicken, purified by affinity chromatography
Szinonimák:
Protein IGO1
Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez
Összes fotó(2)
About This Item
UNSPSC kód:
12352203
eCl@ss:
32160702
NACRES:
NA.41
klón:
polyclonal
application:
IHC
WB
WB
faj reaktivitás:
rat
technika/technikák:
immunohistochemistry: suitable (paraffin)
western blot: suitable
western blot: suitable
citations:
24
Javasolt termékek
biológiai forrás
chicken
Minőségi szint
antitest forma
affinity purified immunoglobulin
antitest terméktípus
primary antibodies
klón
polyclonal
tisztítva
affinity chromatography
faj reaktivitás
rat
faj reaktivitás (homológia által előrejelzett)
mouse (immunogen homology)
technika/technikák
immunohistochemistry: suitable (paraffin)
western blot: suitable
izotípus
IgY
NCBI elérési szám
UniProt elérési szám
kiszállítva
wet ice
célzott transzláció utáni módosítás
unmodified
Általános leírás
Monocarboxylate Transporter 1 (MCT1), also known as Solute carrier family 16 member 1 (SLC16A1), catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Monocarboxylate Transporter 1 is located in the cell membrane, and is widely expressed in both normal and cancer cells. Monocarboxylate Transporter 1 is involved in symptomatic deficiency in lactate transport (SDLT).
Egyediség
This antibody recognizes the C-terminus of Monocarboxylate Transporter 1.
Immunogén
Epitope: C-terminus
KLH-conjugated linear peptide corresponding to the C-terminus of rat Monocarboxylate Transporter 1.
Alkalmazás
Anti-Monocarboxylate Transporter 1 Antibody is a highly specific chicken polyclonal antibody, that targets MCT1 & has been tested in western blotting & IHC (Paraffin).
Immunohistochemistry Analysis: A 1:2,500 dilution from a representative lot detected rat skeletal muscle and rat renal cortex tissues.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Signaling Neuroscience
Signaling Neuroscience
Minőség
Evaluated by Western Blot in rat brain membrane tissue lysate.
Western Blotting Analysis: 0.5 µg/mL of this antibody detected rat brain membrane tissue lysate in 10 µg of rat brain membrane tissue lysate.
Western Blotting Analysis: 0.5 µg/mL of this antibody detected rat brain membrane tissue lysate in 10 µg of rat brain membrane tissue lysate.
Cél megnevezése
Bands are observed at ~44 kDa and ~55 kDa This protein has been observed at ~47 kDa (Sepponen, K., et al. (2003). Acta Physiol Scand. 177(1):79-86.). In addition this protein has been observed at ~55 kDa in certain cell lysates, except in the rumen where two distinct bands appear at ~47 kDa and ~55 kDa (Koho, N., et al. (2005). Comp Biochem Physiol A Mol Integr Physiol. 141(1):29-34.). It is also known to be glycosylated (Carpenter, L., et al. (1996). Biochim Biophys Acta. 1279(2):157-163).
Kapcsolódás
Replaces: AB1286
Fizikai forma
Affinity purified
Purified chicken polyclonal IgY in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Tárolás és stabilitás
Stable for 1 year at 2-8°C from date of receipt.
Analízis megjegyzés
Control
Rat brain membrane tissue lysate
Rat brain membrane tissue lysate
Egyéb megjegyzések
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Jogi nyilatkozat
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Tárolási osztály kódja
12 - Non Combustible Liquids
WGK
WGK 1
Lobbanási pont (F)
Not applicable
Lobbanási pont (C)
Not applicable
Analitikai tanúsítványok (COA)
Analitikai tanúsítványok (COA) keresése a termék sarzs-/tételszámának megadásával. A sarzs- és tételszámok a termék címkéjén találhatók, a „Lot” vagy „Batch” szavak után.
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Az Ön által nemrégiben megvásárolt termékekre vonatkozó dokumentumokat a Dokumentumtárban találja.
Nigel P Moore et al.
International journal of cell biology, 2016, 2084252-2084252 (2016-11-16)
The distribution of monocarboxylate transporter (MCT) isoforms 1 and 4, which mediate the plasmalemmal transport of l-lactic and pyruvic acids, has been identified in the placentae of rats and rabbits at different ages of gestation. Groups of three pregnant Sprague-Dawley
Chang Cao et al.
Current developments in nutrition, 5(4), nzab025-nzab025 (2021-05-04)
The placenta transports iron to the fetus to support growth and development. Mice are commonly used to study placental iron transport. The subcellular locations of transferrin receptor and ferroportin 1 in iron-transporting cells in the mouse placenta have not been
Markus Durst et al.
NMR in biomedicine, 29(8), 1079-1087 (2016-06-28)
Most tumours exhibit a high rate of glycolysis and predominantly produce energy by lactic acid fermentation. To maintain energy production and prevent toxicity, the lactate generated needs to be rapidly transported out of the cell. This is achieved by monocarboxylate
Chongliang Zhong et al.
Animal nutrition (Zhongguo xu mu shou yi xue hui), 10, 216-222 (2022-07-06)
Urea nitrogen secreted from blood to rumen is a crucial factor shaping the symbiotic relationship between host ruminants and their microbial populations. Passage of urea across rumen epithelia is facilitated by urea transporter B (UT-B), but the long-term regulation of
Gabriel N Valbuena et al.
Molecular neurobiology, 53(4), 2222-2240 (2015-05-13)
Defects in energy metabolism are potential pathogenic mechanisms in amyotrophic lateral sclerosis (ALS), a rapidly fatal disease with no cure. The mechanisms through which this occurs remain elusive and their understanding may prove therapeutically useful. We used metabolomics and stable
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