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654380

Sigma-Aldrich

Tunicamycin

from Strepomyces lysosuperficus, ≥98% (A+B+C+D, HPLC), powder, N-acetylglucosamine transferase, Calbiochem

Szinonimák:

Tunicamycin, Streptomyces lysosuperficus

Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez
Összes fotó(1)

About This Item

Tapasztalati képlet (Hill-képlet):
C39H64N4O16
CAS-szám:
11089-65-9
Molekulatömeg:
844.94
MDL-szám:
MFCD00065709
UNSPSC kód:
12352200
NACRES:
NA.77

product name

Tunicamycin, Streptomyces lysosuperficus,

leírás

Tunicamycin, Streptomyces lysosuperficus

Minőségi szint

200

Teszt

≥98% (A+B+C+D, HPLC)

form

powder

gyártó/kereskedő neve

Calbiochem®

oldhatóság

DMSO: 10 mg/mL
DMF: soluble
pyridine: soluble

kiszállítva

ambient

tárolási hőmérséklet

2-8°C

InChI

1S/C30H46N4O16/c1-11(2)5-4-6-16(38)32-19-23(43)20(40)14(47-29(19)50-28-18(31-12(3)36)22(42)21(41)15(10-35)48-28)9-13(37)26-24(44)25(45)27(49-26)34-8-7-17(39)33-30(34)46/h4,6-8,11,13-15,18-29,35,37,40-45H,5,9-10H2,1-3H3,(H,31,36)(H,32,38)(H,33,39,46)/b6-4+/t13?,14-,15-,18-,19-,20+,21-,22-,23-,24+,25-,26-,27-,28-,29-/m1/s1

Nemzetközi kémiai azonosító kulcs

ZHSGGJXRNHWHRS-PEALBESXSA-N

Általános leírás

A nucleoside antibiotic that inhibits N-linked glycosylation and blocks the formation of N-glycosidic protein-carbohydrate linkages. Active in vitro against Gram-positive bacteria, yeasts, fungi, and viruses. Inhibits the expression of functional thrombin receptors on human T-lymphoblastoid cells. Also inhibits thrombin-induced Ca2+ mobilization in cells. Also available as a 25 mM solution in DMSO (Cat. No. 504570).
A nucleoside antibiotic that inhibits N-linked glycosylation and blocks the formation of N-glycosidic protein-carbohydrate linkages. Active in vitro against gram-positive bacteria, yeasts, fungi, and viruses. Inhibits the expression of functional thrombin receptors on human T-lymphoblastoid cells. Also inhibits thrombin-induced Ca2+ mobilization in cells.

Biokémiai/fiziológiai hatások

Primary Target
N-linked glycosylation
Secondary Target
thrombin-induced Ca2+ mobilization in cells

Figyelmeztetés

Toxicity: Highly Toxic & Carcinogenic / Teratogenic (I)

Elkészítési megjegyzés

Aqueous solutions can be prepared from DMSO stock solutions by diluting in H₂O at pH 8.0 to 10.0 or with appropriate buffers at pH >7.0.

Feloldás

Aqueous solutions can be prepared from stock solutions in DMSO by diluting with H₂O at pH 8.0 to 10.0 or with appropriate buffers at pH >7.0 (preferably >8.0).
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 weeks at -20°C.

Egyéb megjegyzések

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Tordai, A., et al. 1995. Biochem. Biophys. Res. Commun. 206, 857.
Price, B.D., et al. 1992. J. Cell Physiol.152, 545.

Jogi információk

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Piktogramok

Skull and crossbones
GHS06

Figyelmeztetés

Danger

Figyelmeztető mondatok

H300

Óvintézkedésre vonatkozó mondatok

P264 - P270 - P301 + P310 - P405 - P501

Veszélyességi osztályok

Acute Tox. 1 Oral

Tárolási osztály kódja

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Lobbanási pont (F)

Not applicable

Lobbanási pont (C)

Not applicable

Analitikai tanúsítványok (COA)

Analitikai tanúsítványok (COA) keresése a termék sarzs-/tételszámának megadásával. A sarzs- és tételszámok a termék címkéjén találhatók, a „Lot” vagy „Batch” szavak után.

Már rendelkezik ezzel a termékkel?

Az Ön által nemrégiben megvásárolt termékekre vonatkozó dokumentumokat a Dokumentumtárban találja.

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