494459

n-Octyl-β-D-glucopyranoside

CAS 29836-26-8 is a non-ionic detergent intended for solubilizing membrane-bound proteins in their native state and for the preparation of lipid vesicles.

• Szinonimák: n-Octyl-β-D-glucopyranoside, OG, n-Octylglucoside
• Tapasztalati képlet (Hill-képlet): C₁₄H₂₈O₆
• CAS-szám: 29836-26-8
• Molekulatömeg: 292.37
• MDL-szám: MFCD00063288
• UNSPSC kód: 12161902
• NACRES: NA.21

Tulajdonságok

• Minőségi szint: 300
• Teszt: ≥98% (HPLC)
• Forma: solid
• gyártó/kereskedő neve: Calbiochem^®
• tárolási körülmény: OK to freeze; desiccated (hygroscopic)
• aggregált szám: 84
• szennyeződések: ≤0.05% n-octanol; ≤35 mg/dL glucose
• szín: white
• CMC: 20 - 25 mM
• oldhatóság: water: 100 mg/mL
• kiszállítva: ambient
• tárolási hőmérséklet: 15-25°C
• SMILES string: O1[C@H]([C@@H]([C@H]([C@@H]([C@H]1CO)O)O)O)OCCCCCCCC
• InChI: 1S/C14H28O6/c1-2-3-4-5-6-7-8-19-14-13(18)12(17)11(16)10(9-15)20-14/h10-18H,2-9H2,1H3/t10-,11-,12+,13-,14-/m1/s1
• Nemzetközi kémiai azonosító kulcs: HEGSGKPQLMEBJL-RKQHYHRCSA-N

Leírás

Általános leírás

Absorbance (10%, H₂O, 260 nm):≤0.3.

Non–ionic detergent intended for solubilizing membrane–bound proteins in their native state and for the preparation of lipid vesicles. Its well–defined chemical structure, small uniform micelles, and high water solubility make it superior to most other nonionic detergents for membrane solubilization. Because of its high critical micelle concentration (20-25 mM), it has the additional advantage of being removed easily by dialysis when compared to bile salts. Aggregation number: 84.

Nonionic detergent intended for solubilizing membrane-bound proteins in their native state and for the preparation of lipid vesicles. Its well-defined chemical structure, small uniform micelles, and high water solubility make it superior to most other nonionic detergents for membrane solubilization. Because of its high critical micelle concentration (20-25 mM), it has the additional advantage of being removed easily by dialysis when compared to bile salts. Aggregation number: 84.

Alkalmazás

• Tube-gel digestion: a novel proteomic approach for high throughput analysis of membrane proteins.: This article introduces a new method for analyzing membrane proteins using tube-gel digestion, which employs n-Octyl-β-D-glucopyranoside for effective solubilization of membrane proteins. This approach enhances the throughput and efficiency of proteomic analyses (Lu et al., 2005).


• Mixed micellization of a nonionic-cationic surfactant system constituted by n-octyl-beta-D-glucopyranoside/dodecyltrimethylammonium bromide/H2O.: The study explores the micellization behavior of a nonionic-cationic surfactant system involving n-Octyl-β-D-glucopyranoside and its interactions. The findings are significant for understanding surfactant properties and applications in biochemical processes (del Burgo et al., 2004).

Figyelmeztetés

Toxicity: Standard Handling (A)

Feloldás

Following reconstitution, store in the refrigerator (4°C), under sterile conditions. Aqueous stock solutions are stable for up to 3 months at 4°C. Solutions are susceptible to hydrolysis (especially acidic solutions) and enzymatic hydrolysis.

Egyéb megjegyzések

Hoshino, T., et al. 1992. J. Biol. Chem.267, 21313.
Levy, D., et al. 1992. Biochim. Biophys. Acta1107, 283.
Nunn, R.S., et al. 1992. J. Mol. Biol.228, 1259.
Lorber, B., et al. 1990. Biochim. Biophys. Acta1023, 254.
Jopski, B., et al. 1989. Biochim. Biophys. Acta978, 79.
Camm, E.L., et al. 1981. Plant Physiol.67, 1061.
Gould, R.J., et al. 1981. Biochemistry20, 6776.

Jogi információk

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Biztonsági adatok

• Tárolási osztály kódja: 13 - Non Combustible Solids
• WGK: WGK 3
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable