494128

Ochratoxin A

≥97% (HPLC), powder, mycotoxin, Calbiochem

• Szinonimák: Ochratoxin A
• Tapasztalati képlet (Hill-képlet): C₂₀H₁₈ClNO₆
• CAS-szám: 303-47-9
• Molekulatömeg: 403.81
• MDL-szám: MFCD00078079
• UNSPSC kód: 12352200
• NACRES: NA.77

Tulajdonságok

• product name: Ochratoxin A, Ochratoxin A (OTA) is a mycotoxin that acts through mechanisms such as the inhibition of protein synthesis, and may also be mediated by organic anion transporters (OATs).
• Minőségi szint: 100
• Teszt: ≥97% (HPLC)
• form: powder
• gyártó/kereskedő neve: Calbiochem^®
• tárolási körülmény: OK to freeze; protect from light
• szín: off-white
• oldhatóság: DMSO: 50 mg/mL, nearly colorless
• kiszállítva: ambient
• tárolási hőmérséklet: 2-8°C
• InChI: 1S/C20H18ClNO6/c1-10-7-12-14(21)9-13(17(23)16(12)20(27)28-10)18(24)22-15(19(25)26)8-11-5-3-2-4-6-11/h2-6,9-10,15,23H,7-8H2,1H3,(H,22,24)(H,25,26)/t10-,15+/m1/s1
• Nemzetközi kémiai azonosító kulcs: RWQKHEORZBHNRI-BMIGLBTASA-N

Leírás

Általános leírás

Ochratoxin A (OTA) is a mycotoxin that acts through mechanisms such as the inhibition of protein synthesis, and may also be mediated by organic anion transporters (OATs).

Ochratoxin A (OTA) is a mycotoxin that acts through mechanisms such as the inhibition of protein synthesis, and may also be mediated by organic anion transporters (OATs). OTA is indicated to play a role in down-regulating the expression of protective enzymes against oxidative stress. It is known to accumulate in several tissues of the body but is primarily localized in the kidney where it impairs proximal tubular functions, and thereby causes nephrotoxicity, glucosuria, enzymuria, and a decrease in the transport of para-aminohippuric acid (PAH). It also acts as an immunosuppressant and as a potent teratogen and carcinogen.

Figyelmeztetés

Toxicity: Highly Toxic & Carcinogenic / Teratogenic (I)

Feloldás

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Egyéb megjegyzések

Anzai, N., et al. 2010. Toxins2, 1381.
Chopra, M., et al. 2010. Cell Biol. Toxicol.26, 239.
Luhe, A., et al. 2002. Tox. Sci.73, 315.
Dirheimer, G., et al. 1991. IARC Swci Publ.115, 171.

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Jogi információk

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Biztonsági adatok

• Piktogramok: GHS06,GHS08
• Figyelmeztetés: Danger
• Figyelmeztető mondatok: H300,H351
• Óvintézkedésre vonatkozó mondatok: P201 - P202 - P264 - P270 - P280 - P301 + P310
• Veszélyességi osztályok: Acute Tox. 2 Oral - Carc. 2
• Tárolási osztály kódja: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable