Q-002

Quetiapine-D₈ hemifumarate solution

100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant^®

• Tapasztalati képlet (Hill-képlet): (C₂₁D₈H₁₇N₃O₂S)₂ · C₄H₄O₄
• CAS-szám: 1435938-24-1
• Molekulatömeg: 899.18
• EC-szám: 200-659-6
• UNSPSC kód: 41116107
• NACRES: NA.24

Tulajdonságok

• grade: certified reference material
• Minőségi szint: 300
• form: liquid
• Jellemzők: Snap-N-Spike^®/Snap-N-Shoot^®
• kiszerelés: ampule of 1 mL
• gyártó/kereskedő neve: Cerilliant^®
• koncentráció: 100 μg/mL in methanol (as free base)
• technika/technikák: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• alkalmazás(ok): clinical testing
• format: single component solution
• tárolási hőmérséklet: −20°C
• SMILES string: OC(=O)\C=C\C(O)=O.[2H]C1([2H])N(CCOCCO)C([2H])([2H])C([2H])([2H])N(C2=Nc3ccccc3Sc4ccccc24)C1([2H])[2H].[2H]C5([2H])N(CCOCCO)C([2H])([2H])C([2H])([2H])N(C6=Nc7ccccc7Sc8ccccc68)C5([2H])[2H]
• InChI: 1S/2C21H25N3O2S.C4H4O4/c2*25-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21;5-3(6)1-2-4(7)8/h2*1-8,25H,9-16H2;1-2H,(H,5,6)(H,7,8)/b;;2-1+/i2*9D2,10D2,11D2,12D2;
• Nemzetközi kémiai azonosító kulcs: ZTHJULTYCAQOIJ-UXUYVNHUSA-N

Leírás

Általános leírás

Quetiapine, marketed as Seroquel^®, is an atypical antipsychotic drug for the treatment of depression, bipolar disorder, and schizophrenia. This new internal standard is applicable to numerous GCMS and LCMS applications including quantitation of patient levels, forensic and forensic toxicology analysis, isotope dilution methods, and calibrator preparation.

Alkalmazás

• Measurement of quetiapine and four quetiapine metabolites in human plasma by LC-MS/MS.: This study presents a robust method for measuring quetiapine and its metabolites using LC-MS/MS, emphasizing the importance of stable isotope-labeled standards like Quetiapine-D8 hemifumarate. This solution is crucial for accurate metabolite analysis, antipsychotic drug research, and pharmacokinetic studies in pharmaceutical and biotechnological research (Fisher et al., 2012).

Jogi információk

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Seroquel is a registered trademark of Astrazeneca UK

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Biztonsági adatok

• Piktogramok: GHS02,GHS06,GHS08
• Figyelmeztetés: Danger
• Figyelmeztető mondatok: H225,H301 + H311 + H331,H370
• Óvintézkedésre vonatkozó mondatok: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Veszélyességi osztályok: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Célzott szervek: Eyes,Central nervous system
• Tárolási osztály kódja: 3 - Flammable liquids
• WGK: WGK 2
• Lobbanási pont (F): 49.5 °F - closed cup
• Lobbanási pont (C): 9.7 °C - closed cup