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Merck
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L-025

Supelco

(−)-Levamisole hydrochloride solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez
Összes fotó(1)

About This Item

Tapasztalati képlet (Hill-képlet):
C11H12N2S
CAS-szám:
16595-80-5
Molekulatömeg:
204.29
MDL-szám:
MFCD00792481
UNSPSC kód:
41116107
PubChem Substance ID:
329817345
NACRES:
NA.24

grade

certified reference material

Minőségi szint

300

form

liquid

Jellemzők

Snap-N-Spike®/Snap-N-Shoot®

kiszerelés

ampule of 1 mL

gyártó/kereskedő neve

Cerilliant®

koncentráció

1.0 mg/mL in methanol (as free base)

technika/technikák

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

alkalmazás(ok)

pharmaceutical (small molecule)

format

single component solution

tárolási hőmérséklet

−20°C

SMILES string

C1CN2C[C@@H](N=C2S1)c3ccccc3

InChI

1S/C11H12N2S/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10/h1-5,10H,6-8H2/t10-/m1/s1

Nemzetközi kémiai azonosító kulcs

HLFSDGLLUJUHTE-SNVBAGLBSA-N

Related Categories

Általános leírás

Levamisole, an antihelminthic drug used to treat worm infestations in humans and animals, is an adulterant and cutting agent found in cocaine sold in the US and Canada. From 2008-2009, levamisole was detected in 69% of cocaine samples seized by the US Drug Enforcement Administration (DEA).

Alkalmazás


  • Immunomodulatory research: The study explored the potential immunomodulatory effects of levamisole hydrochloride in humans and farm animals, highlighting its utility in enhancing immune responses and its therapeutic potential across a range of conditions (Gholami et al., 2023).

  • Anthelmintic research: A study developed a real-time detection method for the levamisole resistance variant in Haemonchus contortus, illustrating the role of levamisole hydrochloride in understanding and managing anthelmintic resistance (Antonopoulos et al., 2024).

Jogi információk

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Figyelmeztetés

Danger

Figyelmeztető mondatok

H225,H301 + H311 + H331,H370

Veszélyességi osztályok

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Célzott szervek

Eyes

Tárolási osztály kódja

3 - Flammable liquids

WGK

WGK 1

Lobbanási pont (F)

49.5 °F - closed cup

Lobbanási pont (C)

9.7 °C - closed cup

Analitikai tanúsítványok (COA)

Analitikai tanúsítványok (COA) keresése a termék sarzs-/tételszámának megadásával. A sarzs- és tételszámok a termék címkéjén találhatók, a „Lot” vagy „Batch” szavak után.

Már rendelkezik ezzel a termékkel?

Az Ön által nemrégiben megvásárolt termékekre vonatkozó dokumentumokat a Dokumentumtárban találja.

Dokumentumtár megtekintése

Anders N Hansen et al.
PloS one, 7(9), e45405-e45405 (2012-10-02)
Inhibition of angiogenesis is a promising addition to current cancer treatment strategies. Neutralization of vascular endothelial growth factor by monoclonal antibodies is clinically effective but may cause side effects due to thrombosis. Low molecular weight angiogenesis inhibitors are currently less
Bashir A Lone et al.
Tropical animal health and production, 45(3), 743-749 (2012-10-16)
The aim of this study was to evaluate the anthelmintic and antimicrobial efficacy of Euphorbia helioscopia crude extracts. A worm motility inhibition assay and egg hatch assay were used for in vitro study, and a faecal egg count reduction assay
Jonathan Graf
Current opinion in rheumatology, 25(1), 50-55 (2012-12-01)
Cocaine use is associated with several rheumatic syndromes. This review summarizes these clinical manifestations and highlights recent developments linked to levamisole-adulterated cocaine. Cocaine use has been linked to several distinctive syndromes that can be difficult to distinguish from idiopathic rheumatic
Lauren Strazzula et al.
Journal of the American Academy of Dermatology, 69(6), 954-959 (2013-10-01)
Levamisole is present as a contaminant or additive in most cocaine sold in the United States. Cases of agranulocytosis attributed to levamisole-tainted cocaine have been widely described. A vasculopathic reaction to levamisole has also been reported; however, diagnostic features such as
Annemarie Rosan Kreeftmeijer-Vegter et al.
Expert opinion on drug delivery, 10(3), 293-300 (2013-01-08)
To develop an oral solid dosage form of levamisole suitable for the paediatric population in terms of dose accuracy, palatability, stability and ease of administration. Small undividable tablets (Ø5 - 8 mm) in four different strengths were manufactured to allow
View All Related Papers

Tudóscsoportunk valamennyi kutatási területen rendelkezik tapasztalattal, beleértve az élettudományt, az anyagtudományt, a kémiai szintézist, a kromatográfiát, az analitikát és még sok más területet.

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