Ugrás a tartalomra
Merck

E-075

Supelco

Estrone solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez


About This Item

Tapasztalati képlet (Hill-képlet):
C18H22O2
CAS-szám:
Molekulatömeg:
270.37
MDL-szám:
UNSPSC kód:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

certified reference material

Minőségi szint

Forma

liquid

Jellemzők

Snap-N-Spike®/Snap-N-Shoot®

kiszerelés

ampule of 1 mL

gyártó/kereskedő neve

Cerilliant®

koncentráció

1.0 mg/mL in methanol

technika/technikák

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

alkalmazás(ok)

clinical testing
clinical testing

Formátum

single component solution

tárolási hőmérséklet

−20°C

SMILES string

CC12CCC3C(CCc4cc(O)ccc34)C1CCC2=O

InChI

1S/C18H22O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-16,19H,2,4,6-9H2,1H3/t14-,15-,16+,18+/m1/s1

Nemzetközi kémiai azonosító kulcs

DNXHEGUUPJUMQT-CBZIJGRNSA-N

Géninformáció

human ... ESR1(2099)

Általános leírás

A precursor of estradiol, estrone is monitored in serum or plasma by LC-MS/MS or GC/MS to assess and diagnose developmental abnormalities, enzyme inactivity or deficiency, polycystic ovary syndrome (PCOS), or hormone replacement therapy in women.

Alkalmazás


  • Fluconazole solution for yeast infection treatment: Fluconazole is extensively utilized for its efficacy against yeast infections, specifically vulvovaginal candidiasis. It operates by inhibiting the synthesis of ergosterol, crucial for fungal cell membrane integrity, thereby exerting its antifungal effects (Picheta et al., 2024).

  • Antifungal medication in systemic candidiasis: Fluconazole solution is critical in treating systemic candidiasis, offering a potent antifungal mechanism that disrupts the fungal cell membrane′s ergosterol content, essential for maintaining fungal cell viability (Dettlaff et al., 2024).

  • Fluconazole in vitro antifungal activity assay development: Fluconazole is utilized in the development of in vitro antifungal activity assays, which are crucial for screening potential antifungal agents and assessing their efficacy against various fungal pathogens (Teba et al., 2024).


Jogi információk

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Figyelmeztetés

Danger

Figyelmeztető mondatok

Veszélyességi osztályok

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Célzott szervek

Eyes,Central nervous system

Tárolási osztály kódja

3 - Flammable liquids

WGK

WGK 2

Lobbanási pont (F)

49.5 °F - closed cup

Lobbanási pont (C)

9.7 °C - closed cup


Analitikai tanúsítványok (COA)

Analitikai tanúsítványok (COA) keresése a termék sarzs-/tételszámának megadásával. A sarzs- és tételszámok a termék címkéjén találhatók, a „Lot” vagy „Batch” szavak után.

Már rendelkezik ezzel a termékkel?

Az Ön által nemrégiben megvásárolt termékekre vonatkozó dokumentumokat a Dokumentumtárban találja.

Dokumentumtár megtekintése

Kiyoshi Ito
The Tohoku journal of experimental medicine, 212(1), 1-12 (2007-04-28)
Hormone replacement therapy (HRT) has become available over the past few decades, but the risk of breast cancer with HRT remains controversial. The Women's Health Initiative Study has recently demonstrated that women receiving estrogen plus progestin (HRT) have an increased
Susannah J Stanway et al.
The oncologist, 12(4), 370-374 (2007-05-02)
Inhibitors of steroid sulfatase are being developed as a novel therapy for hormone-dependent breast cancer in postmenopausal women. Data suggest that steroid sulfatase (STS) activity is much higher than aromatase activity in breast tumors and high levels of STS mRNA
Emma M Ferguson et al.
Water research, 47(4), 1604-1615 (2013-01-12)
Estuaries are often the final repositories for aquatic pollutants but how estuarine hydrology influences the availability of marine- and freshwater-derived pollutants is not well understood, particularly for micro-pollutants such as endocrine disrupting chemicals. To address this knowledge gap, this study
Eva Fetter et al.
Aquatic toxicology (Amsterdam, Netherlands), 154, 221-229 (2014-06-14)
Xenoestrogens may persist in the environment by binding to sediments or suspended particulate matter serving as long-term reservoir and source of exposure, particularly for organisms living in or in contact with sediments. In this study, we present for the first
Xavier Remesar et al.
Medicinal research reviews, 32(6), 1263-1291 (2011-02-03)
Oleoyl-estrone (OE) is a powerful slimming agent that is also present in plasma and adipose tissue, where it is synthesized. It acts through the formation of a derivative W. OE effects (and W levels) are proportional to the dose. OE

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