890900O

ALC-0315

Avanti Research^™ - A Croda Brand

• Szinonimák: ALC 0315, 6-((2-hexyldecanoyl)oxy)-N-(6-((2-hexyldecanoyl)oxy)hexyl)-N-(4-hydroxybutyl)hexan-1-aminium
• Tapasztalati képlet (Hill-képlet): C₄₈H₉₅NO₅
• Molekulatömeg: 766.27
• MDL-szám: MFCD33402175
• UNSPSC kód: 12352211
• NACRES: NA.25

Tulajdonságok

• Forma: oil
• kiszerelés: pkg of 1x1 g (890900O-1G); pkg of 1x100 mg (890900O-100MG); pkg of 1x200 mg (890900O-200MG); pkg of 1x25 mg (890900O-25MG); pkg of 1x50 mg (890900O-50MG); pkg of 1x500 mg (890900O-500MG)
• gyártó/kereskedő neve: Avanti Research^™ - A Croda Brand
• technika/technikák: thin layer chromatography (TLC): suitable
• alkalmazás(ok): advanced drug delivery
• lipidtípus: cationic lipids
• kiszállítva: dry ice
• tárolási hőmérséklet: −20°C
• SMILES string: O=C(C(CCCCCC)CCCCCCCC)OCCCCCCN(CCCCO)CCCCCCOC(C(CCCCCCCC)CCCCCC)=O
• InChI: 1S/C48H95NO5/c1-5-9-13-17-19-27-37-45(35-25-15-11-7-3)47(51)53-43-33-23-21-29-39-49(41-31-32-42-50)40-30-22-24-34-44-54-48(52)46(36-26-16-12-8-4)38-28-20-18-14-10-6-2/h45-46,50H,5-44H2,1-4H3

Leírás

Alkalmazás

• Cationic Lipid Pairs Enhance Liver-to-Lung Tropism of Lipid Nanoparticles for In Vivo mRNA Delivery.: ALC-0315 plays a critical role in this study, enhancing the delivery efficiency of mRNA therapies from liver to lung. This research could lead to improved treatment options for various pulmonary diseases (Zeng et al., 2024).


• Engineering LNPs with polysarcosine lipids for mRNA delivery.: Demonstrates ALC-0315′s application in designing lipid nanoparticles that efficiently deliver mRNA, showcasing potential advancements in gene therapy (Kang et al., 2024).


• Tumor-activated IL-2 mRNA delivered by lipid nanoparticles for cancer immunotherapy.: Utilizes ALC-0315 in the development of lipid nanoparticles that activate under tumor-specific conditions to deliver immunotherapeutic agents, offering a targeted approach to cancer treatment (Jiang et al., 2024).

Kiszerelés

• 5 mL Amber Glass Screw Cap Vial (890900O-25MG)
• 5 mL Amber Glass Screw Cap Vial (890900O-50MG)
• 5 mL Amber Glass Screw Cap Vial (890900O-100MG)
• 5 mL Amber Glass Screw Cap Vial (890900O-200MG)
• 5 mL Amber Glass Screw Cap Vial (890900O-500MG)
• 30 mL Amber Glass Screw Cap Vial(890900O-1G)

Egyéb megjegyzések

Quantities limited to 50G in a calendar year per customer.

Jogi információk

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Biztonsági adatok

• Tárolási osztály kódja: 10 - Combustible liquids
• WGK: WGK 3
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable