Ugrás a tartalomra
Merck

192066

Sigma-Aldrich

Poly(2-hydroxyethyl methacrylate)

average Mv 300,000, crystalline

Szinonimák:

Poly(2-HEMA), Poly-HEMA

Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez


About This Item

Lineáris képlet:
(C6H10O3)n
CAS-szám:
MDL-szám:
UNSPSC kód:
12162002
PubChem Substance ID:
NACRES:
NA.23

Forma

crystalline

Minőségi szint

molekulatömeg

average Mv 300,000

sűrűség

1.15 g/mL at 25 °C (lit.)

SMILES string

CC(=C)C(=O)OCCO

InChI

1S/C6H10O3/c1-5(2)6(8)9-4-3-7/h7H,1,3-4H2,2H3

Nemzetközi kémiai azonosító kulcs

WOBHKFSMXKNTIM-UHFFFAOYSA-N

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Általános leírás

Solid Poly(2-hydroxyethyl methacrylate) (pHEMA) is brittle, while pHEMA hydrogel is a soft material. Glass transition temperature for pHEMA hydrogels is reduced by increasing a content of water in the matrix. Macromolecular properties in pHEMA are characterized by non-covalent interactions of hydrogen-bonds among the polymer chains as well as the hydrated water molecules. The presence of polar groups of hydroxyl and carboxyl on each repeat unit makes this polymer compatible with water. The hydrophobic a-methyl groups of the backbone convey hydrolytic stability to the polymer and enhance mechanical strength of the polymer matrix.

Alkalmazás

pHEMA scaffolds are used in tissue engineering. It can be used in hydrogels for biomedical applications, as sorbents for metal ions.pHEMA has been used in applications such as soft contact lenses, in drug delivery systems, and in kidney dialysis membranes.Nanoparticles of pHEMA may be employed as a carrier for controlled delivery of anticancer and antitumor drugs.

Fizikai forma

Water-swellable polymer. Hydrogel.

Tárolási osztály kódja

11 - Combustible Solids

WGK

WGK 3

Lobbanási pont (F)

Not applicable

Lobbanási pont (C)

Not applicable

Egyéni védőeszköz

Eyeshields, Gloves, type N95 (US)


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Analitikai tanúsítványok (COA)

Lot/Batch Number

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Dokumentumtár megtekintése

Fiber templating of poly (2-hydroxyethyl methacrylate) for neural tissue engineering
Flynn L,et al
Biomaterials, 24(23), 4265-4272 null
W E Roorda et al.
Pharmaceutical research, 5(11), 722-725 (1988-11-01)
The freezing and melting behavior of water in poly hydroxy ethyl methacrylate (pHEMA) hydrogels of different cross-linker and water contents was investigated in relation to the glass transition temperature (Tg) of the gels. After prolonged cooling at -15 degrees C
Xiangling Meng et al.
Journal of biomedical materials research. Part A, 101(4), 1095-1102 (2012-09-26)
The objective of the present in vitro study was to investigate cardiomyocyte functions, specifically their adhesion and proliferation, on injectable scaffolds containing RNT (rosette nanotubes) and CNF (carbon nanofibers) in a pHEMA (poly(2-hydroxyethyl methacrylate)) hydrogel to determine their potential for
Amit D Bhrany et al.
JAMA facial plastic surgery, 15(1), 29-33 (2013-01-19)
To evaluate the performance of a sphere-templated poly(2-hydroxyethyl methacrylate) (poly[HEMA]) tissue scaffold as a subcutaneous implant by comparing it with widely used high-density porous polyethylene (HDPPE) implant material. We implanted sphere-templated porous poly-(HEMA) and HDPPE disks into the dorsal subcutis
Yunfeng Li et al.
ACS applied materials & interfaces, 5(6), 2126-2132 (2013-02-23)
This paper presents a versatile way to prepare multiscale and gradient patterns of proteins. The protein patterns are fabricated by conjugating proteins covalently on patterns of polymer brush that are prepared by techniques combining colloidal lithography with photolithography, and two-step

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Protocols

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