ESR1

estrogen receptor 1

Sinonimi:

ER, ESR, ESRA, ESTRR, Era, NR3A1

Specie:

Human ESR1 (2099), Mouse Esr1 (13982), Rat Esr1 (24890), domestic cat ESR1 (552888), dog ESR1 (403640), chicken ESR1 (396099), Thale Cress ESR1 (837856), Horse ESR1 (791249), Zebrafish esr1 (259252), cow ESR1 (407238) ...Più

ID UniProtKB:

P03372, Q13511, Q14276, Q5T5H7, Q6MZQ9, Q9NU51, Q9UDZ7, Q9UIS7

ID gene:

Human(2099) Summary: This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters. [provided by RefSeq, Jul 2008]
Mouse(13982) estrogen receptor 1 (alpha)
Rat(24890) estrogen receptor 1
domestic cat(552888) estrogen receptor 1
dog(403640) estrogen receptor 1
chicken(396099) estrogen receptor 1
Thale Cress(837856) ethylene-responsive transcription factor ESR1
Horse(791249) estrogen receptor 1
Zebrafish(259252) estrogen receptor 1
cow(407238) estrogen receptor 1
Goat(100860768) estrogen receptor 1
sheep(443228) estrogen receptor 1
domestic guinea pig(100713276) estrogen receptor 1

Prodotti (195)
Documenti “peer reviewed” (1,024)

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Small Molecule - Activator

N° Catalogo

Descrizione

Specie

131083

4-Phenylazophenol, 98%,

Specie

human

N0632

β-Nicotinamide adenine dinucleotide sodium salt, ,

Specie

human

139939

trans-Stilbene, 96%,

Specie

human, rat

N7004

β-Dinucleotide nicotinamide adenina, ≥96.5% (HPLC), ≥96.5% (spectrophotometric assay), from yeast,

Specie

human

43410

β-Dinucleotide nicotinamide adenina, ≥95% (HPLC),

Specie

human

Small Molecule - Agonist

N° Catalogo

Descrizione

Specie

E-060

17β-Estradiol solution, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant^®,

Specie

human

1250008

Estradiol, United States Pharmacopeia (USP) Reference Standard,

Specie

human

PHR1480

Ethinyl Estradiol, Pharmaceutical Secondary Standard; Certified Reference Material,

Specie

human

E-075

Estrone solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®,

Specie

human

1260001

Ethinyl estradiol, United States Pharmacopeia (USP) Reference Standard,

Specie

human

Small Molecule - Allosteric Modulator

N° Catalogo

Descrizione

Specie

85256

Tamoxifene, analytical standard,

Specie

human

1643306

Tamoxifen citrate, United States Pharmacopeia (USP) Reference Standard,

Specie

human

06734

Tamoxifene, certified reference material, TraceCERT^®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland,

Specie

human

BP1225

Tamoxifen citrate, British Pharmacopoeia (BP) Reference Standard,

Specie

human

T0014000

Tamoxifen citrate, European Pharmacopoeia (EP) Reference Standard,

Specie

human

Small Molecule - Antagonist

N° Catalogo

Descrizione

Specie

524980

Dibutilftalato, 99%,

Specie

mouse

Z2125

Zearalenone, fungal mycotoxin,

Specie

mouse

308501

Benzyl butyl phthalate, 98%,

Specie

mouse

290823

4-tert-Octylphenol, 97%,

Specie

mouse

49085

Atrazine, analytical standard,

Specie

mouse

Antibodies

N° Catalogo

Descrizione

Reattività con

Applicazione

HPA000449

Anti-ESR1 antibody produced in rabbit, Prestige Antibodies^® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,

Reattività con

human

Applicazione

immunofluorescence
immunohistochemistry
western blot

SAB4500813

Anti-Estrogen Receptor-α antibody produced in rabbit, affinity isolated antibody,

Reattività con

human

Applicazione

ELISA
immunohistochemistry
western blot

04-1564

Anti-Estrogen Receptor α Antibody, clone F3-A, ascites fluid, clone F3-A, from mouse,

Reattività con

human, mouse, rat

Applicazione

immunocytochemistry
western blot

AMAB90867

Monoclonal Anti-ESR1 antibody produced in mouse, Prestige Antibodies^® Powered by Atlas Antibodies, clone CL1196, purified immunoglobulin, buffered aqueous glycerol solution,

Reattività con

human

Applicazione

immunofluorescence
immunohistochemistry
western blot

07-662

Anti-Estrogen-related Receptor α Antibody, Upstate^®, from rabbit,

Reattività con

hamster, human, mouse, rat

Applicazione

electrophoretic mobility shift assay
immunohistochemistry
immunoprecipitation (IP)
western blot