This product has not been tested for solubility in DMSO, however various sources report that it is soluble at 20 mg/mL.
E1024
Estradiol
meets USP testing specifications
Sinonimo/i:
β-Estradiol, 1,3,5-Estratriene-3,17β-diol, 17β-Estradiol, 3,17β-Dihydroxy-1,3,5(10)-estratriene, Dihydrofolliculin
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1 G
CHF 125.00
25 G
CHF 1’850.00
100 G
CHF 6’640.00
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Cambia visualizzazione
1 G
CHF 125.00
25 G
CHF 1’850.00
100 G
CHF 6’640.00
About This Item
Formula empirica (notazione di Hill):
C18H24O2
Numero CAS:
Peso molecolare:
272.38
Beilstein:
1914275
Numero CE:
Numero MDL:
Codice UNSPSC:
12352104
ID PubChem:
NACRES:
NA.21
Prodotti consigliati
agenzia
USP/NF
meets USP testing specifications
Livello qualitativo
Forma fisica
powder
Punto di fusione
176-180 °C (lit.)
applicazioni
pharmaceutical (small molecule)
Stringa SMILE
O[C@H]1CC[C@@]2([H])[C@]3([H])CCC4=CC(O)=CC=C4[C@@]3([H])CC[C@@]21C
InChI
1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m1/s1
VOXZDWNPVJITMN-ZBRFXRBCSA-N
Informazioni sul gene
human ... ESR1(2099) , ESR2(2100) , ESRRB(2103) , GPER(2852) , SERPINA6(866)
mouse ... Esr1(13982) , Esr2(13983) , Esrra(26379)
rat ... Afp(24177) , Ar(24208) , Esr1(24890) , Esr2(25149) , Shbg(24775)
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Categorie correlate
Azioni biochim/fisiol
The major estrogen secreted by the premenopausal ovary. Estrogens direct the development of the female phenotype in embryogenesis and during puberty by regulating gene transcription and, thus, protein synthesis. It also induces the production of gonadotropins which, in turn, induce ovulation. Exposure to estradiol increases breast cancer incidence and proliferation.
Avvertenze
Danger
Indicazioni di pericolo
Consigli di prudenza
Classi di pericolo
Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Lact. - Repr. 1A
Codice della classe di stoccaggio
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Dispositivi di protezione individuale
Eyeshields, Gloves, type P2 (EN 143) respirator cartridges
Certificati d'analisi (COA)
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Fiona C Baker et al.
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It is believed that sex hormones are synthesized in the gonads and reach the brain via the blood circulation. In contrast with this view, the authors have demonstrated that sex hormones are also synthesized locally in the hippocampus and that
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Premenstrual dysphoric disorder (PMDD) is the prototypical sex-specific disorder in which symptom onset and offset require a particular hormonal milieu and for which there is moderate heritability. The present study investigated brain emotion processing in PMDD and healthy controls, as
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Is product E1024 soluble in DMSO? If so, what is the recommended initial stock concentration to make?
1 answer-
Helpful?
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What is Product E1024, Estradiol, soluble in?
1 answer-
It is soluble in ethanol, acetone, dioxane, and sparingly in vegetable oils.
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What is the solution stability of Product E1024, Estradiol?
1 answer-
Since this material is air sensitive, it is best to prepare solutions fresh.
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What is the Department of Transportation shipping information for this product?
1 answer-
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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What is the working range of Product E1024, Estradiol?
1 answer-
For cell culture applications, the working range of this compound is 0.2 - 10 ng/mL. For cell culture tested beta-estradiol, please refer to Sigma-Aldrich Prod. Nos. E2758 and E2257.
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