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Z2125

Sigma-Aldrich

Zearalenone

fungal mycotoxin

Sinonimo/i:

F-2 toxin

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About This Item

Formula empirica (notazione di Hill):
C18H22O5
Numero CAS:
17924-92-4
Peso molecolare:
318.36
Beilstein:
1350216
Numero MDL:
MFCD00133085
Codice UNSPSC:
12191503
ID PubChem:
24902175
NACRES:
NA.77

Livello qualitativo

300

Temperatura di conservazione

−20°C

Stringa SMILE

C[C@H]1CCCC(=O)CCC\C=C\c2cc(O)cc(O)c2C(=O)O1

InChI

1S/C18H22O5/c1-12-6-5-9-14(19)8-4-2-3-7-13-10-15(20)11-16(21)17(13)18(22)23-12/h3,7,10-12,20-21H,2,4-6,8-9H2,1H3/b7-3+/t12-/m0/s1
MBMQEIFVQACCCH-QBODLPLBSA-N

Informazioni sul gene

mouse ... Esr1(13982)

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Categorie correlate

Azioni biochim/fisiol

Zearalenone, a fungal mycotoxin produced by Fusarium, binds the estrogen receptor (ER) and is uterotropic in the newborn rat. It is a common contaminant in cereal grain used for animal and human food, and exerts an estrogenic activity that modulates/disrupts endocrine function in animals and possibly humans.

Pittogrammi

Health hazardCorrosion
GHS08,GHS05

Avvertenze

Danger

Indicazioni di pericolo

H314,H361d

Classi di pericolo

Eye Dam. 1 - Repr. 2 - Skin Corr. 1B

Codice della classe di stoccaggio

8A - Combustible corrosive hazardous materials

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

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α-Zearalanol ~98% (HPLC)

Sigma-Aldrich

Z0292

α-Zearalanol

T-2 Toxin from Fusarium sp., powder, ≥98% (HPLC)

Sigma-Aldrich

T4887

T-2 Toxin

Curvularin from Penicillium citrinum, ≥98% (HPLC)

Sigma-Aldrich

SML0772

Curvularin

Deoxynivalenol solution 100 μg/mL in acetonitrile, analytical standard

Supelco

34124

Deoxynivalenol solution

vibrant-m

ERMAC699

Zearalenone in acetonitrile

D M Sheehan et al.
Teratology, 29(3), 383-392 (1984-06-01)
Fusarium sp. contaminated feedstuffs elicit adverse estrogenic effects in several commercially important animal species via the mycotoxin zearalenone. An estrogenically active synthetic derivative, zearalanol, is used as an anabolic agent in cattle. Since estrogens can irreversibly alter target tissue development
Katarzyna Cieplińska et al.
Toxins, 11(5) (2019-05-30)
Zearalenone is a frequent contaminant of cereals and their by-products in regions with a temperate climate. This toxic molecule is produced naturally by Fusarium fungi in crops. The aim of this study was to determine the influence of low zearalenone
H Leffers et al.
Human reproduction (Oxford, England), 16(5), 1037-1045 (2001-05-02)
We have compared the oestrogenic potency of the synthetic oestrogen Zeranol, used as a growth promoter in meat production, and five related compounds, with the potency of 17beta-oestradiol, diethylstilboestrol (DES), genistein, and Bisphenol-A. The potency was assayed by analysing differences
Kazimierz Obremski et al.
Toxins, 12(6) (2020-05-31)
The aim of the present study was to determine the effect of zearalenone (ZEN), administered per os to gilts at doses equivalent to 50%, 100%, and 150% of no-observed-adverse-effect level (NOAEL) values for 14, 28, and 42 days during weaning
Cristina Juan et al.
Food chemistry, 134(4), 2389-2397 (2013-02-28)
Although analytical methods have been already reported for legislated mycotoxins as trichothecenes and zearalenone (ZON) separately, we describe the optimization of a simple and rapid multimycotoxin method for the determination of a total of 12 mycotoxins simultaneously, nine trichothecenes (NIV
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