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Merck
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Documenti

85256

Supelco

Tamoxifene

analytical standard

Sinonimo/i:

(Z)-1-(p-Dimetilamminoetossifenil)-1,2-difenil-1-butene, trans-2-[4-(1,2-difenil-1-butenil)fenossi]-N,N-dimetiletilammina

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About This Item

Formula condensata:
C6H5C(C2H5)=C(C6H5)C6H4OCH2CH2N(CH3)2
Numero CAS:
10540-29-1
Peso molecolare:
371.51
Numero CE:
234-118-0
Numero MDL:
MFCD00010454
Codice UNSPSC:
41116107
ID PubChem:
329769367
NACRES:
NA.24

Grado

analytical standard

Livello qualitativo

100

Saggio

≥98.0% (HPLC)

Durata

limited shelf life, expiry date on the label

tecniche

HPLC: suitable
gas chromatography (GC): suitable

Impurezze

≤0.5% water

Punto di fusione

97-98 °C (lit.)

applicazioni

forensics and toxicology
pharmaceutical (small molecule)

Formato

neat

Temperatura di conservazione

2-8°C

Stringa SMILE

CC\C(c1ccccc1)=C(/c2ccccc2)c3ccc(OCCN(C)C)cc3

InChI

1S/C26H29NO/c1-4-25(21-11-7-5-8-12-21)26(22-13-9-6-10-14-22)23-15-17-24(18-16-23)28-20-19-27(2)3/h5-18H,4,19-20H2,1-3H3/b26-25-
NKANXQFJJICGDU-QPLCGJKRSA-N

Informazioni sul gene

human ... ESR1(2099)

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Categorie correlate

Applicazioni

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Azioni biochim/fisiol

Inibitore della protein-chinasi C Induce l′apoptosi in cellule di glioma maligno umano. Il tamoxifene e il suo metabolita 4-idrossitamoxifene sono modificatori selettivi della risposta agli estrogeni (SERM) che agiscono come antagonisti degli estrogeni nella ghiandola mammaria. Blocca la produzione di VEGF stimolata dall'estradiolo nelle cellule di cancro al seno.

Pittogrammi

Health hazardEnvironment
GHS08,GHS09

Avvertenze

Danger

Indicazioni di pericolo

H350,H360,H410

Consigli di prudenza

P201 - P273 - P308 + P313

Classi di pericolo

Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1A - Repr. 1B

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Choose from one of the most recent versions:

Certificati d'analisi (COA)

Lot/Batch Number
BCCL6241
BCCK6230
BCCH5113
BCCG8921
BCCC8810

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Supelco

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Sigma-Aldrich

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Sigma-Aldrich

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Supelco

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Sigma-Aldrich

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Sigma-Aldrich

608645

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Sigma-Aldrich

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Sigma-Aldrich

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