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Red yeast rice repairs kidney damage and reduces inflammatory transcription factors in rat models of hyperlipidemia.

Red yeast rice repairs kidney damage and reduces inflammatory transcription factors in rat models of hyperlipidemia.

Experimental and therapeutic medicine (2014-11-06)

Mei Ding, Daoyuan Si, Wenqi Zhang, Zhaohui Feng, Min He, Ping Yang

ZUSAMMENFASSUNG

Xuezhikang (XZK), an extract of red yeast rice, has been widely used for the management of hyperlipidemia and coronary heart disease (CHD); however, the effects of XZK treatment on kidney injury have not yet been fully identified. The aim of the current study was to evaluate the effects of XZK on the kidneys and investigate the related mechanisms in a rat model of hyperlipidemia. Thus, the effect on inflammatory transcription factors and kidney damage was investigated with

MATERIALIEN

Produktnummer

Marke

Produktbeschreibung

Sigma-Aldrich

Cholesterin, Sigma Grade, ≥99%

Sigma-Aldrich

Cholecalciferol, ≥98% (HPLC)

Sigma-Aldrich

Cholesterin, powder, BioReagent, suitable for cell culture, ≥99%

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3,3′,5,5′-Tetramethylbenzidin, ≥99%

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Cholesterin, from sheep wool, ≥92.5% (GC), powder

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4,4′-Diaminodiphenylmethan, ≥97.0% (GC)

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3,3′,5,5′-Tetramethylbenzidin, ≥98% (TLC)

Supelco

Cholecalciferol (D3), analytical standard

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SyntheChol^® NS0-Supplement, 500 ×, synthetic cholesterol, animal component-free, aqueous solution, sterile-filtered, suitable for cell culture

USP

Cholecalciferol, United States Pharmacopeia (USP) Reference Standard

Supelco

Cholesterin -Lösung, certified reference material, 10 mg/mL in chloroform

Supelco

Vitamin D3 solution, 1 mg/mL in ethanol, ampule of 1 mL, certified reference material, Cerilliant^®

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3,3′,5,5′-Tetramethylbenzidin, ≥98.0% (NT)

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Cholecalciferol (Vitamin D3), Pharmaceutical Secondary Standard; Certified Reference Material

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3,3′,5,5′-Tetramethylbenzidin, tablet, 1 mg substrate per tablet

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Vitamin D₃ solution, 100 μg/mL in ethanol, 97% (CP)

Supelco

Cholesterin, Pharmaceutical Secondary Standard; Certified Reference Material

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Cholesterin, from lanolin, ≥99.0% (GC)

SAFC

Cholesterin, from sheep wool, Controlled origin, meets USP/NF testing specifications

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β-D-Allose, rare aldohexose sugar

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Cholecalciferol, meets USP testing specifications

Cholecalciferol, European Pharmacopoeia (EP) Reference Standard

Sigma-Aldrich

Cholecalciferol, analytical standard

Supelco

4,4′-Diaminodiphenylmethan, analytical standard

Sigma-Aldrich

Cholesterin, tested according to Ph. Eur.

Supelco

3,3′,5,5′-Tetramethylbenzidin, standard for GC