900601

3-Formyl-5-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride

≥95%

• Synonym(e): Formyl sulfonyl fluoride alkyne, Probe building block
• Empirische Formel (Hill-System): C₁₂H₁₃FO₃SSi
• CAS-Nummer: 2088829-13-2
• Molekulargewicht: 284.38
• UNSPSC-Code: 12352200
• NACRES: NA.22

Eigenschaften

• Assay: ≥95%
• Form: solid
• Eignung der Reaktion: reaction type: click chemistry
• Lagertemp.: −20°C
• SMILES String: O=C([H])C1=CC(S(=O)(F)=O)=CC(C#C[Si](C)(C)C)=C1

Beschreibung

Anwendung

3-Formyl-5-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride is used for chemical probe synthesis, this trifunctional building block contains an aryl sulfonyl fluoride group, alkyne tag, and aldehyde synthetic handle. When appended to a ligand or pharmacophore through its formyl group, this building block allows for SuFEx-enabled, context-specific covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

Sonstige Hinweise

Technology Spotlight: Trifuctional Probe Building Blocks

Chemoselective Preparation of Clickable Aryl Sulfonyl Fluoride Monomers: A Toolbox of Highly Functionalized Intermediates for Chemical Biology Probe Synthesis

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable