301035

[Hydroxy-(tosyloxy)-iod]-benzol

96%

• Synonym(e): Hydroxy-(4-methylbenzolsulfonat-O)-phenyliod, Iodosobenzol-J-mono-(p-toluolsulfonat), Koser’s Reagens
• Lineare Formel: CH₃C₆H₄SO₃I(OH)C₆H₅
• CAS-Nummer: 27126-76-7
• Molekulargewicht: 392.21
• Beilstein: 2150074
• MDL-Nummer: MFCD00011547
• UNSPSC-Code: 12352002
• PubChem Substanz-ID: 24858159
• NACRES: NA.22

Eigenschaften

• Assay: 96%
• Eignung der Reaktion: reagent type: oxidant
• mp (Schmelzpunkt): 131-137 °C (lit.)
• SMILES String: Cc1ccc(cc1)S(=O)(=O)O[I](O)c2ccccc2
• InChI: 1S/C13H13IO4S/c1-11-7-9-13(10-8-11)19(16,17)18-14(15)12-5-3-2-4-6-12/h2-10,15H,1H3
• InChIKey: LRIUKPUCKCECPT-UHFFFAOYSA-N

Beschreibung

Anwendung

Reactant for:

• Ligand-free palladium-catalyzed Heck-type coupling reactions
• Preparation of carbodiimides via dehydrosulfurization of thioureas
• Preparation of nitriles by oxidative conversion of alcohols, aldehydes, and amines
• Preparation of substituted anilines via aromatic aldoxime reaction
• Preparation of tetrahydrofurans by oxidative cyclization of homoallylic alcohols
• Preparation of isoxazoline N-Oxides from ß-hydroxyketoximes via oxidative N-O coupling
• Ring expansion in synthesis of aminopeptidase inhibitors
• Oxidation and protonation reactions in acidic conditions

Widely used oxidant in the synthesis of various organic compounds.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319
• P-Sätze: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves