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Documentos Principais

1044006

USP

Ácido acetilsalicílico

United States Pharmacopeia (USP) Reference Standard

Sinônimo(s):

Ácido O-acetilsalicílico, AAS, Aspirina, Ácido 2-acetoxibenzoico

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About This Item

Fórmula linear:
2-(CH3CO2)C6H4CO2H
Número CAS:
Peso molecular:
180.16
Beilstein:
779271
Número MDL:
Código UNSPSC:
41116107
ID de substância PubChem:
NACRES:
NA.24
O produto 1044006 é um produto específico do cliente e não está disponível para venda na Internet. Entre em contato com a assistência técnica

grau

pharmaceutical primary standard

família API

aspirin

fabricante/nome comercial

USP

pf

134-136 °C (lit.)

aplicação(ões)

pharmaceutical (small molecule)

Formato

neat

cadeia de caracteres SMILES

CC(=O)Oc1ccccc1C(O)=O

InChI

1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12)

chave InChI

BSYNRYMUTXBXSQ-UHFFFAOYSA-N

Informações sobre genes

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Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

Aspirin USP reference standard suitable for use in specified USP compendial quality tests and assays.

Also used to prepare standard solution for impurity analysis and performance test according to the given below monographs of United States Pharmacopeia (USP):
  • Carisoprodol and Aspirin Tablets. [1]
  • Aspirin Tablets. [2]
  • Aspirin Boluses. [3]
  • Butalbital, Aspirin, Caffeine, and Codeine Phosphate Capsules. [4]

Ações bioquímicas/fisiológicas

Bloqueia a produção de prostaglandinas pela inibição da ciclo-oxigenase (prostaglandina H sintase), com maior seletividade para a isoforma COX-1. O efeito antitrombótico se deve à inibição de COX-1 nas plaquetas que bloqueiam a produção de tromboxano e a agregação de plaquetas. Atividade quimiopreventiva contra tumores colorretais e outros tumores sólidos.

Nota de análise

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Outras notas

Sales restrictions may apply.

Pictogramas

Exclamation mark

Palavra indicadora

Warning

Frases de perigo

Declarações de precaução

Classificações de perigo

Acute Tox. 4 Oral

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

482.0 °F

Ponto de fulgor (°C)

250 °C


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Certificados de análise (COA)

Lot/Batch Number

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Sigma-Aldrich

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Sigma-Aldrich

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Aspirin Boluses
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 42(4), 388-388 (2017)
Butalbital, Aspirin, Caffeine, and Codeine Phosphate Capsules
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 46(2), 648-648 (2013)
Aspirin Tablets
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 42(4), 392-392 (2020)
Carisoprodol and Aspirin Tablets
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 778-778 (2013)
Laurent Arnaud et al.
Autoimmunity reviews, 13(3), 281-291 (2013-11-06)
We performed a meta-analysis to determine whether aspirin has a significant protective effect on risk of first thrombosis among patients with antiphospholipid antibodies (aPL+). Observational and interventional studies identified from the Medline, Embase and Cochrane databases were selected if they

Questions

1–2 of 2 Questions  
  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

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