T3396
Tetraglycol
BioXtra
Sinônimo(s):
Glycofurol, Tetrahydrofurfuryl alcohol polyethyleneglycol ether
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About This Item
Preço e disponibilidade não estão disponíveis no momento.
Produtos recomendados
descrição
non-ionic
linha de produto
BioXtra
Formulário
liquid (clear)
Impurezas
<0.5% water (Coulometric)
<5 ppm heavy metal
cor
colorless to light yellow
pf
≤ -100 °C
solubilidade
water: soluble 3420 g/L
densidade
1.09 g/mL at 25 °C (lit.)
cadeia de caracteres SMILES
O1C(CCC1)COCCO
InChI
1S/C7H14O3/c8-3-5-9-6-7-2-1-4-10-7/h7-8H,1-6H2
chave InChI
CTPDSKVQLSDPLC-UHFFFAOYSA-N
Aplicação
Tetraglycol has been used:
- to dilute DiI (1,1′-dioctadecyl-3,3,3′3′-tetramethylindocarbocyanine perchlorate) for injecting fertilized chicken eggs for DiI labeling
- to dilute DiI (1,1′-dioctadecyl-3,3,3′3′-tetramethylindocarbocyanine perchlorate) and diO (3,3′-dioctadecyloxacarbocyanine perchlorate) for dye/virus injections
- to dilute poly (lactide-co-glycolide) (PLGA) to prepare PLGA/F127 solution
Used as solvent to dissolve water-insoluble compounds.
Ações bioquímicas/fisiológicas
Liquid glycofurol can readily transform into gel systems with excellent elasticity due to which, it can be used as a medium to dissolve water-insoluble drugs.
Características e benefícios
Efficient solubilizer for glibenclamide (GBD)
Atenção
Do not confuse with tetraethylene glycol, which is also sometimes called tetraglycol.
Outras notas
To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.
Palavra indicadora
Warning
Frases de perigo
Declarações de precaução
Classificações de perigo
Eye Irrit. 2
Código de classe de armazenamento
10 - Combustible liquids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
275.0 °F - closed cup
Ponto de fulgor (°C)
135 °C - closed cup
Equipamento de proteção individual
Eyeshields, Gloves
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Saly Galal et al.
Acta pharmaceutica (Zagreb, Croatia), 53(1), 57-64 (2004-02-11)
The ability of liquid and semi-solid matrix (SSM) filling capsule technology to improve the dissolution rate of glibenclamide (GBD) was investigated. Semiquantitative estimation of GBD solubility in various vehicles was carried out. Tetraglycol was found to be the most efficient
X F Zhang et al.
Materials science & engineering. C, Materials for biological applications, 32(6), 1654-1663 (2012-08-01)
Poly (lactide-co-glycolide) (PLGA) - Pluronic F127 - glass composites have demonstrated excellent potential, from the perspective of controlled mechanical properties and cytocompatibility, for peripheral nerve regeneration. In addition to controlling the mechanical properties and cytotoxicity for such composite devices, the
Nahla Salah Barakat
AAPS PharmSciTech, 11(3), 1138-1146 (2010-07-24)
In view of the good skin tolerability, glycofurol was used as a vehicle-based gel, and its effect in the topical penetration of Naproxen (NAP) was investigated. The aims of this study were to develop a suitable gel with bioadhesive property
S Kehoe et al.
Journal of the mechanical behavior of biomedical materials, 14, 180-185 (2012-10-03)
PLGA/pluronic F127 based nerve guidance conduits (NGCs) for peripheral nerve regeneration offer excellent potential for clinical use. To date, little emphasis has been directed towards the effect of pluronic F127 on their subsequent mechanical properties as a function of degradation
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